Evidence map›Paper›PMID 32438245›Full record

ArticleVeterinary immunology and immunopathology2020

Immune response and onset of protection from Bovine viral diarrhea virus 2 infection induced by modified-live virus vaccination concurrent with injectable trace minerals administration in newly received beef calves.

João H J Bittar, Roberto A Palomares, David J Hurley, Alejandro Hoyos-Jaramillo, Adriana Rodriguez, Agne Stoskute, Brianna Hamrick, Natalie Norton, Morgan Adkins, Jeremiah T Saliki and 2 more

Open access · greenAbstract read
In one paragraph

Article in Veterinary immunology and immunopathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Trace Mineral Nutrition of Grazing Beef Cattle.Animals : an open access journal from MDPI · 2021
    Review
  8. Review
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

João H J BittarDepartment of Population Health, College of Veterinary Medicine, University of Georgia, Athens, GA, 30602-2771, United States; Group for Reproduction in Animals, Vaccinology and Infectious Diseases (GRAVID(TM)), United States; Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, 32610, United States.
Roberto A PalomaresDepartment of Population Health, College of Veterinary Medicine, University of Georgia, Athens, GA, 30602-2771, United States; Department of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, GA, 30602-2771, United States; Group for Reproduction in Animals, Vaccinology and Infectious Diseases (GRAVID(TM)), United States. Electronic address: palomnr@uga.edu.
David J HurleyDepartment of Population Health, College of Veterinary Medicine, University of Georgia, Athens, GA, 30602-2771, United States; Department of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, GA, 30602-2771, United States.
Alejandro Hoyos-JaramilloDepartment of Population Health, College of Veterinary Medicine, University of Georgia, Athens, GA, 30602-2771, United States; Group for Reproduction in Animals, Vaccinology and Infectious Diseases (GRAVID(TM)), United States.
Adriana RodriguezDepartment of Population Health, College of Veterinary Medicine, University of Georgia, Athens, GA, 30602-2771, United States; Group for Reproduction in Animals, Vaccinology and Infectious Diseases (GRAVID(TM)), United States.
Agne StoskuteGroup for Reproduction in Animals, Vaccinology and Infectious Diseases (GRAVID(TM)), United States.
Brianna HamrickGroup for Reproduction in Animals, Vaccinology and Infectious Diseases (GRAVID(TM)), United States.
Natalie NortonDepartment of Large Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens, GA, 30602-2771, United States.
Morgan AdkinsDepartment of Population Health, College of Veterinary Medicine, University of Georgia, Athens, GA, 30602-2771, United States.
Jeremiah T SalikiAthens Veterinary Diagnostic Laboratory, College of Veterinary Medicine, University of Georgia, Athens, GA, 30602-2771, United States.
Susan SanchezAthens Veterinary Diagnostic Laboratory, College of Veterinary Medicine, University of Georgia, Athens, GA, 30602-2771, United States.
Kensey LauberGroup for Reproduction in Animals, Vaccinology and Infectious Diseases (GRAVID(TM)), United States.
University of Georgia · USInstitute for Animal Reproduction · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Strategies to improve the onset of protective immunity induced by vaccination against respiratory pathogens may have a significant impact on health of newly received beef calves. The objective was to determine if the use of injectable trace minerals (ITM; Se, Zn, Cu, and Mn) concurrent with a modified-live virus (MLV) vaccine enhances the immune response and onset of protection in beef calves challenged with BVDV2 five days after vaccination. Forty-five calves were randomly assigned to one of three groups (15/group): VAC + ITM, received MLV-vaccine and ITM (Multimin®90) subcutaneously (SC); VAC + SAL, received the same vaccine and saline SC; or UNVAC, unvaccinated. Five days after vaccination (d.0), calves were challenged with BVDV2 strain 890. Health status was evaluated and blood samples were collected for leukocyte counts, BVDV1 and 2 serum neutralizing antibodies (SNA), BVDV-PCR, and percentage of CD4

Indexed as

Age FactorsAnimalsAntibodies, NeutralizingAntibodies, ViralBovine Virus Diarrhea-Mucosal DiseaseCattleCattle DiseasesDiarrhea Virus 2, Bovine ViralTrace ElementsVaccinationVaccines, AttenuatedViral VaccinesAntibodies, NeutralizingAntibodies, ViralTrace ElementsVaccines, AttenuatedViral VaccinesBeef calvesBVDVModified-live virus vaccineProtectionTrace minerals

Identifiers

PMID32438245
PMCPMC7184996
OpenAlexW3021601077

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.