Evidence map›Paper›PMID 32438236›Full record

ArticleClinical imaging2020

Intraductal papillary neoplasm of the bile duct (IPNB): CT and MRI appearance with radiology-pathology correlation.

Anum Aslam, Ashish P Wasnik, Jiaqi Shi, Vaibhav Sahai, Mishal Mendiratta-Lala

Open access · greenAbstract read
In one paragraph

Article in Clinical imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 28 citations in OpenAlex.

  1. European journal of nuclear medicine and molecular imaging · 2026
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  10. [Magnetic resonance imaging features and classification of intraductal papillary neoplasm of the bile duct].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2024
    Article
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  16. Mucin-producing Cystic Hepatobiliary Neoplasms: Updated Nomenclature and Clinical, Pathologic, and Imaging Features.Radiographics : a review publication of the Radiological Society of North America, Inc · 2021
    Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Anum AslamPGY 7, University of Michigan Health System, 1500 E. Medical Center Dr., Ann Arbor, MI 48109-5030, United States of America. Electronic address: aanum@med.umich.edu.
Ashish P WasnikAbdominal Radiology, Michigan Medicine, United States of America. Electronic address: ashishw@med.umich.edu.
Jiaqi ShiDepartment of Pathology, Michigan Medicine, United States of America. Electronic address: Jiaqis@med.umich.edu.
Vaibhav SahaiDepartment of Internal Medicine, Division of Hematology/Oncology, United States of America. Electronic address: vsahai@med.umich.edu.
Mishal Mendiratta-LalaAbdominal and Cross-Sectional Interventional Radiology, Michigan Medicine, United States of America. Electronic address: mmendira@med.umich.edu.
Michigan Medicine · USUniversity of Michigan–Ann Arbor · US

Funding

Linking epigenetic regulation and TGF-β signaling in pancreatic cancerK08CA234222 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SHI, JIAQI · 2018 to 2021
$744k
NCI NIH HHS K08 CA234222
6 · The paper itself

Abstract

purposeIntraductal papillary neoplasm of the bile duct (IPNB) is a precursor to invasive carcinoma and is a distinct pathologic diagnosis. The purpose of this study was to evaluate imaging features of IPNB on cross-sectional imaging studies with histopathologic correlation. MATERIALS AND

methodsIn this IRB approved, HIPAA compliant retrospective observational analysis of 23 pathology proven IPNB tumors 22 imaging studies were reviewed, 14 CT and 8 MRI scans. Features evaluated in consensus by two subspecialty-trained abdominal radiologists included: presence of specific lesion/mass within the bile duct, location within the biliary tree, size, morphology, enhancement characteristics, and bile duct caliber.

resultsMajority of the subjects (16/18, 90%) had definite intraluminal mass, of which 7 (39%) had a polypoid mass with upstream diffuse biliary ductal dilation and 5 (28%) had a plaque-like mass with focal stricture and upstream biliary ductal dilatation. 6/18 (33%) subjects had low grade dysplasia, most commonly intestinal subtype, 7/18 (39%) subjects presented with invasive component, commonly pancreaticobiliary subtype, and 5/18 (28%) presented with high grade dysplasia.

conclusionIPNB has increased predilection for extrahepatic bile ducts, commonly presenting as either an intraluminal polypoidal mass with associated upstream biliary ductal dilation or a focal plaque like mass with associated ductal stricture at the site of the tumor.

Indexed as

Bile Duct NeoplasmsBile Ducts, ExtrahepaticBile Ducts, IntrahepaticCarcinoma, PapillaryFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedRadiographyRetrospective StudiesTomography, X-Ray ComputedCholangiocarcinomaExtra hepatic polypoidal massFrond-likeIntraductal papillary neoplasm of bile ductPlaque-like stricturePremalignant

Identifiers

PMID32438236
PMCPMC7577174
OpenAlexW3023300823

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.