ArticleBiological psychology2020
Low cardiac vagal control is associated with genetic liability for elevated triglycerides and risky health behaviors.
Article in Biological psychology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- Nonlinear Relations Between Resting Heart Rate Measures and Health Risk Behavior in Emerging Adulthood.Journal of adolescence · 2026Article
- Discrimination and anxiety: Using multiple polygenic scores to control for genetic liability.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
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Authors and funding
3 authors.
Funding
Abstract
Low parasympathetic regulation of cardiac activity, known as cardiac vagal control (CVC), is robustly associated with poor health outcomes. However, the etiological mechanism that undergirds this association remains largely unknown. One explanation is a causal relationship wherein health problems cause low CVC, or vice versa. However, an alternative explanation is that a common set of genetic factors contributes to both increased liability for poor health and low CVC (i.e., pleiotropy). The present study uses polygenic risk scores for a number of health-related phenotypes (physical, mental, behavioral) to test whether genetic liability for poor health has pleiotropic effects on CVC. We report evidence for shared genetic liability between low CVC and both poor physical health (elevated triglycerides) and risky health-related behaviors (increased drinking and sexual activity). The present findings are consistent with shared genetic liability explaining, at least in part, the well-documented correlation between CVC and health.
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