Evidence map›Paper›PMID 32437757›Full record

ArticleThe Journal of pediatrics2020

Treatment Discontinuation within 3 Years of Levothyroxine Initiation among Children Diagnosed with Congenital Hypothyroidism.

Alex R Kemper, Scott D Grosse, Mei Baker, Allison J Pollock, Cynthia F Hinton, Stuart K Shapira

Abstract readMulticenter Study
In one paragraph

Article in The Journal of pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Review
  5. Evidence and recommendation for mucopolysaccharidosis type II newborn screening in the United States.Genetics in medicine : official journal of the American College of Medical Genetics · 2023
    Review
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alex R KemperDivision of Primary Care Pediatrics, Nationwide Children's Hospital, Columbus, OH. Electronic address: alex.kemper@nationwidechildrens.org.
Scott D GrosseNational Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA.
Mei BakerDepartment of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Allison J PollockDepartment of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI.
Cynthia F HintonNational Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA.
Stuart K ShapiraNational Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA.

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

objectivesTo measure the rates of thyroid gland imaging and levothyroxine (L-T STUDY

designThis is a retrospective analysis of claims data from the IBM MarketScan Databases for children born between 2010 and 2016 and continuously enrolled in a noncapitated employer-sponsored private health insurance plan or in Medicaid for ≥36 months from the date of the first filled L-T

resultsThere were 263 privately insured and 241 Medicaid-enrolled children who met the inclusion criteria. More privately insured than Medicaid-enrolled children had imaging between the first filled prescription and 180 days after the last filled prescription (24.3% vs 12.9%; P = .001). By 36 months, 35.7% discontinued L-T

conclusionsNearly one-third of children with suspected congenital hypothyroidism discontinued L-T

Indexed as

Guideline AdherenceWithholding TreatmentCongenital HypothyroidismFemaleFollow-Up StudiesHormone Replacement TherapyHumansInfantInfant, NewbornMalePrognosisRetrospective StudiesThyroxineTime FactorsThyroxine

Identifiers

PMID32437757
PMCPMC7427425

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.