ArticleAmerican journal of ophthalmology2020
Epidemiology and Clinical Characteristics of Episcleritis and Scleritis in Olmsted County, Minnesota.
Article in American journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 31 citations in OpenAlex.
- Clinical characteristics, management, and visual outcomes of presumed infectious and non-infectious anterior scleritis in a tuberculosis-endemic Indonesian Tertiary Center.International ophthalmology · 2026Article
- Blood-Ocular Barrier Dysfunction in Uveitis: A Bidirectional Model Linking Pathogenesis, Clinical Monitoring, and Therapeutic Opportunities.Medical sciences (Basel, Switzerland) · 2026Review
- Efficacy and tolerability of subcutaneous repository corticotropin injection in refractory ocular inflammatory diseases.Journal of ophthalmic inflammation and infection · 2024Article
- Understanding Health Care Disparities Based on Medicare Use for Inflammatory and Infectious Eye Diseases.Translational vision science & technology · 2024Article
- Posterior Scleritis in a Pediatric Patient: Importance of Pain Recognition and Early Ultrasound Diagnosis.Cureus · 2024Article
- Management of Scleritis in Older Adults.Drugs & aging · 2024Article
- Configurations associated with the efficiency of the ophthalmology departments in public hospitals of Central South China.PloS one · 2024Article
- Posterior scleritis following COVID-19 vaccination or infection simulating uveal melanoma in 8 consecutive patients.Eye (London, England) · 2024Article
- Next-generation nanomaterials: advancing ocular anti-inflammatory drug therapy.Journal of nanobiotechnology · 2023Review
- Characteristics and Outcomes of Patients with Scleritis in the IRIS® Registry (Intelligent Research in Sight) Database.Ophthalmology science · 2022Article
- Article
- Methotrexate for chronic non-necrotizing anterior scleritis in Chinese patients.International journal of ophthalmology · 2022Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
purposeTo determine the population-based incidence and disease associations of episcleritis and scleritis in a midwestern U.S. POPULATION:
designPopulation-based retrospective cohort study.
methodsAll residents of Olmsted County, Minnesota from 2006 to 2015 were identified by using the Rochester Epidemiology Project. A total of 223 episcleritis cases and 77 scleritis cases were identified. The incidence and disease associations of episcleritis and scleritis were assessed, as well as scleritis recurrence rates, treatment, and complications.
resultsIncidence rates for episcleritis and scleritis were 15.39 and 5.54 per 100,000 per year, respectively. Females accounted for 60.1% of episcleritis and 51.9% of scleritis cases. The mean age at diagnosis was 40.2 years of age for episcleritis and 48.8 years of age for scleritis. In the episcleritis cases, the incidence in females was higher (P = .01). There were no significant differences between sexes for scleritis incidence (P = .75); 23.4% of scleritis patients had an associated systemic disease. Patients with systemic disease showed a trend toward an increased risk of recurrence, but it was not statistically significant. There was a slightly decreased risk of scleritis recurrence with older age at diagnosis (hazard ratio [HR]: 0.73; P = .058; 95% confidence interval [CI]: 0.52-1.01). At last follow-up, most eyes with scleritis (90.4%) had good visual acuity (better than 20/40), and 92.3% had stable or improved visual acuity.
conclusionsThe Olmsted County, Minnesota population had a lower incidence of episcleritis and a higher incidence of scleritis than populations in previous studies. The population-based results from the current study may provide information that is more applicable to a primary eye care setting.
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