Evidence map›Paper›PMID 32437656›Full record

ArticleNeuron2020

Deep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer's Disease Progression.

Bing Bai, Xusheng Wang, Yuxin Li, Ping-Chung Chen, Kaiwen Yu, Kaushik Kumar Dey, Jay M Yarbro, Xian Han, Brianna M Lutz, Shuquan Rao and 24 more

Abstract readPublished Erratum
In one paragraph

Article in Neuron, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

34 authors.

Bing Bai
Xusheng Wang
Yuxin Li
Ping-Chung Chen
Kaiwen Yu
Kaushik Kumar Dey
Jay M Yarbro
Xian Han
Brianna M Lutz
Shuquan Rao
Yun Jiao
Jeffrey M Sifford
Jonghee Han
Minghui Wang
Haiyan Tan
Timothy I Shaw
Ji-Hoon Cho
Suiping Zhou
Hong Wang
Mingming Niu
Ariana Mancieri
Kaitlynn A Messler
Xiaojun Sun
Zhiping Wu
Vishwajeeth Pagala
Anthony A High
Wenjian Bi
Hui Zhang
Hongbo Chi
Vahram Haroutunian
Bin Zhang
Thomas G Beach
Gang Yu
Junmin Peng

Funding

Research Education ComponentP30AG019610 · NIA · SUN HEALTH RESEARCH INSTITUTE · PI REIMAN, ERIC MICHAEL · 2001 to 2020
$32.5M
Integrative Network Biology Approaches to Identify, Characterize and Validate Molecular Subtypes in Alzheimer's DiseaseU01AG046170 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WANG, MINGHUI, ZHANG, BIN · 2013 to 2022
$26.0M
National Brain and Tissue Resource for Parkinson's Disease and Related DisordersU24NS072026 · NINDS · BANNER SUN HEALTH RESEARCH INSTITUTE · PI BEACH, THOMAS G · 2011 to 2015
$7.8M
Systems Approaches to Novel Molecular Mechanism in Alzheimer's DiseaseRF1AG064909 · NIA · UT SOUTHWESTERN MEDICAL CENTER · PI PENG, JUNMIN, YU, GANG · 2019 to 2024
$6.4M
Integrative Network Modeling of Cognitive Resilience to Alzheimer's DiseaseR01AG057907 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI EHRLICH, MICHELLE E, HAROUTUNIAN, VAHRAM · 2017 to 2021
$6.3M
Towards a comprehensive signaling pathway map of parahippocampal vulnerability in Alzheimers DiseaseRF1AG057440 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HAROUTUNIAN, VAHRAM, NOGGLE, SCOTT ALLEN · 2017 to 2017
$3.5M
Multi-level Integrative Proteomics to Alzheimer's Disease PathwaysR01AG053987 · NIA · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI PENG, JUNMIN · 2016 to 2020
$2.2M
RNA splicing dysfunction in Alzheimer's diseaseR01AG047928 · NIA · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI PENG, JUNMIN · 2015 to 2019
$1.8M
Gamma-Secretase and Myelin: A Paradigm Shift in Brain DisordersR01NS079796 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI YU, GANG · 2013 to 2017
$1.7M
Proteomics Approaches to Protein TurnoverR01GM114260 · NIGMS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI PENG, JUNMIN · 2016 to 2019
$1.4M
NIA NIH HHS P30 AG019610NIA NIH HHS R01 AG047928NIA NIH HHS R01 AG053987NIA NIH HHS R01 AG057907NIA NIH HHS RF1 AG057440NIA NIH HHS RF1 AG064909NIA NIH HHS U01 AG046170NIGMS NIH HHS R01 GM114260NINDS NIH HHS R01 NS079796NINDS NIH HHS U24 NS072026
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID32437656
PMCPMC7322979

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.