Evidence map›Paper›PMID 32437362›Full record

ArticlePloS one2020

Acute kidney injury in critically ill cancer patients is associated with mortality: A retrospective analysis.

Nina Seylanova, Siobhan Crichton, Jing Zhang, Richard Fisher, Marlies Ostermann

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In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Understanding cancer disease status and what it means for intensivists.Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nina SeylanovaDepartment of Critical Care, King's College London, Guy's & St Thomas' Hospital Foundation Trust, London, United Kingdom.ORCID 0000-0001-7523-5427
Siobhan CrichtonMedical Research Council Clinical Trials Unit, University College London, London, United Kingdom.
Jing ZhangDepartment of Critical Care, King's College London, Guy's & St Thomas' Hospital Foundation Trust, London, United Kingdom.
Richard FisherDepartment of Critical Care, King's College Hospital, London, United Kingdom.
Marlies OstermannDepartment of Critical Care, King's College London, Guy's & St Thomas' Hospital Foundation Trust, London, United Kingdom.ORCID 0000-0001-9500-9080

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn critically ill patients, acute kidney injury (AKI) is common and associated with short- and long-term complications. Our objectives were to describe the epidemiology and impact of AKI in cancer patients admitted to the Intensive Care Unit (ICU).

methodsWe identified all patients with a haematological malignancy (HM) or solid tumour (ST) who had an emergency admission to the ICU in a tertiary care centre between January 2004 and July 2012. AKI was defined according to the KDIGO criteria.

results429 patients were included of whom 259 (60%) had AKI. Among HM patients, 73 (78%) had AKI (70% AKI on admission to ICU; 7% during ICU stay); among ST patients, 186 (56%) had AKI (45% on admission to ICU, 11% during ICU stay). ICU and 28-day mortality rates were 33% and 48%, respectively in HM patients, and 22% and 31%, respectively in ST patients. Multivariable analysis showed that AKI was an independent risk factor for both ICU and 28-day mortality. New AKI after 24 hours in ICU was associated with higher mortality than AKI on admission.

conclusionsAKI is common in critically ill cancer patients and independently associated with ICU and 28-day mortality.

Indexed as

Critical IllnessAcute Kidney InjuryAgedFemaleHumansIntensive Care UnitsMaleMiddle AgedNeoplasmsRetrospective StudiesRisk Factors

Identifiers

PMID32437362
PMCPMC7241809

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.