ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2020
Potentially inappropriate medications use and its association with health-related quality of life among elderly cardiac patients.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Lists of potentially inappropriate medications for older people in primary care: a systematic review of health outcomes.Cadernos de saude publica · 2024Pooled it
- The current view of potentially inappropriate medications (PIMs) among older adults in Saudi Arabia: a systematic review.Frontiers in pharmacology · 2023Pooled it
- Potentially Inappropriate Medications and Drug-Drug Interactions in Geriatrics Cardiac Patients Visiting to Tertiary Care Central Hospital of Nepal.Aging medicine (Milton (N.S.W)) · 2025Article
- Quality of prescribing and health-related quality of life in older adults: a narrative review with a special focus on patients with atrial fibrillation and multimorbidity.European geriatric medicine · 2025Review
- Investigating the impact of a pharmacist intervention on inappropriate prescribing practices at hospital admission and discharge in older patients: a secondary outcome analysis from a randomized controlled trial.Therapeutic advances in drug safety · 2024Article
- Potentially Inappropriate Medications Use among Older Adults with Dyslipidaemia.Journal of clinical medicine · 2023Article
- Gender Differences in Potentially Inappropriate Medication Use among Older Adults.Pharmaceuticals (Basel, Switzerland) · 2023Article
- Article
- Overuse of medications in low- and middle-income countries: a scoping review.Bulletin of the World Health Organization · 2023Article
- Health-related quality of life and its predictors among adults living with HIV/AIDS and receiving antiretroviral therapy in Pakistan.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021Article
- Reassessment of Treatments in a Long-Term Care Unit.Gerontology & geriatric medicineArticle
- Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious studies identified alarming use of potentially inappropriate medications (PIMs) in Pakistani population but its effect on health-related quality of life (HRQoL) is still largely unknown.
objectiveThis study aimed to determine the association between PIMs use and HRQoL among elderly cardiac outpatients.
methodA descriptive, non-experimental, cross-sectional study was carried out from June 2018 to September 2018 in two outpatient departments of tertiary-care hospitals in the Punjab Province of Pakistan. The population under study were patients aged ≥ 65 years with at least one cardiovascular condition taking at ≥ 1 prescribed medication. Patients with PIMs were identified by using Beers criteria. HRQoL was assessed using EuroQoL-5 dimension (EQ-5D) and EuroQoL-visual analogue scale (EQ-VAS). The association of PIMs with HRQoL was analyzed using χ
resultsOf 386 elderly cardiac patients, 260 (67.4%) patients were receiving at least one PIM. Mean EQ-5D scores were significantly lower among patients with PIMs (0.51) compared to patients without PIMs (0.65) (P < 0.001). In multiple linear regression analysis, increasing numbers of PIMs were significantly associated with lower EQ-5D scores [β = - 0.040 (- 0.075, - 0.005), P < 0.001] and VAS scores [β = - 1.686 (- 2.916, - 0.456), P < 0.05].
conclusionThe present study concluded that exposure to PIM was significantly associated with lower HRQoL. This indicates that guidelines recommendations should be followed to improve patient's quality of life.
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