Evidence map›Paper›PMID 32436073›Full record

ArticleWorld journal of urology2021

Seasonal variations in overactive bladder drug prescription rates in women: a nationwide population-based study.

Jong Won Kim, Hyun Kyu Ahn, Jongcheol Ko, Dongu Lee, Jee Soo Ha, Jae Hwan Kim, So Jeong Park, Kang Su Cho

Abstract read
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In one paragraph

Article in World journal of urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jong Won KimDepartment of Urology, Gangnam Severance Hospital, Yonsei University College of Medicine, 211 Eonju-ro, Gangnam-gu, Seoul, 06273, Korea.ORCID https://orcid.org/0000-0002-0449-228X
Hyun Kyu AhnDepartment of Urology, Gangnam Severance Hospital, Yonsei University College of Medicine, 211 Eonju-ro, Gangnam-gu, Seoul, 06273, Korea.ORCID https://orcid.org/0000-0002-1996-6249
Jongcheol KoDepartment of Urology, Gangnam Severance Hospital, Yonsei University College of Medicine, 211 Eonju-ro, Gangnam-gu, Seoul, 06273, Korea.ORCID https://orcid.org/0000-0002-7583-4910
Dongu LeeDepartment of Urology, Gangnam Severance Hospital, Yonsei University College of Medicine, 211 Eonju-ro, Gangnam-gu, Seoul, 06273, Korea.ORCID https://orcid.org/0000-0002-0959-0233
Jee Soo HaDepartment of Urology, Gangnam Severance Hospital, Yonsei University College of Medicine, 211 Eonju-ro, Gangnam-gu, Seoul, 06273, Korea.ORCID https://orcid.org/0000-0002-3923-4619
Jae Hwan KimData Science Team, Hanmi Pharmaceutical. Co. Ltd., Seoul, Korea.ORCID https://orcid.org/0000-0001-7283-2293
So Jeong ParkData Science Team, Hanmi Pharmaceutical. Co. Ltd., Seoul, Korea.ORCID https://orcid.org/0000-0001-6019-6912
Kang Su ChoDepartment of Urology, Gangnam Severance Hospital, Yonsei University College of Medicine, 211 Eonju-ro, Gangnam-gu, Seoul, 06273, Korea. kscho99@yuhs.ac.ORCID http://orcid.org/0000-0002-3500-8833

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeColder seasons can aggravate lower urinary tract symptoms, especially an overactive bladder (OAB). This aspect has been extensively studied in men and rarely in women. We investigated whether colder seasons influence OAB-drug prescription rates (OAB-DPRs) in women.

methodsWomen aged > 18 years were selected from the Korean Health Insurance Review and Assessment Service-National Patient Sample data between 2012 and 2016. OAB-DPR was calculated according to age and seasonal groups. The prescription rates in summer (June, July, and August) and winter (January, February, and December) months were compared. Sub-analysis was performed according to age group.

resultsIn total, 3,061,343 adult women were included. The overall OAB-DPR was 3.75% (114,940/3,061,343). Overall OAB-DPRs in summer and winter were 1.41% (43,090/3,061,343) and 1.54% (47,038/3,061,343), respectively (p < 0.001). Seasonal variations in OAB-DPRs differed by age group (p < 0.001): OAB-DPRs were significantly lower in winter than in summer months in women aged < 50 years (odds ratio 0.942; 95% confidence interval 0.918-0.967; p < 0.001), but significantly higher in winter than in summer months in women aged ≥ 50 years (odds ratio 1.153; 95% confidence interval 1.135-1.171; p < 0.001).

conclusionIn this study, a correlation was noted between OAB-DPR and seasons. OAB-DPRs were higher in the summer in women aged < 50 years and higher in the winter in women aged ≥ 50 years. Our findings suggest that female hormonal status may be involved in the contradictory effect of seasons on OAB symptoms.

Indexed as

SeasonsAdultAgedAged, 80 and overDrug PrescriptionsFemaleHumansMiddle AgedRepublic of KoreaUrinary Bladder, OveractiveOveractiveSeasonsUrinary bladderVariationWomen

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.