Evidence map›Paper›PMID 32436011›Full record

Trial reportJournal of thrombosis and thrombolysis2020

Anemone study: prevalence of risk factors for superficial vein thrombosis in a large Italian population of blood donors.

Elvira Grandone, Giovanni Luca Tiscia, Angelo Ostuni, Lazzaro di Mauro, Mario Mastroianno, Nadia Coffetti, Roberto Dovigo, Giovanna Meneghini, Anna Turrini, Giobatta Cavallero and 6 more

Abstract readClinical TrialMulticenter Study
PubMed Publisher
In one paragraph

Trial report in Journal of thrombosis and thrombolysis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Superficial Venous Thrombosis: A Comprehensive Review.Healthcare (Basel, Switzerland) · 2024
    Review
  2. Hormones and thrombosis: the dark side of the moon.Blood transfusion = Trasfusione del sangue · 2024
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 2 countries.

Elvira GrandoneThrombosis and Haemostasis Unit, Fondazione IRCCS "Casa Sollievo della Sofferenza", Viale Cappuccini, 71013, San Giovanni Rotondo, Italy. e.grandone@operapadrepio.it.ORCID http://orcid.org/0000-0002-8980-9783
Giovanni Luca TisciaThrombosis and Haemostasis Unit, Fondazione IRCCS "Casa Sollievo della Sofferenza", Viale Cappuccini, 71013, San Giovanni Rotondo, Italy.
Angelo OstuniTransfusion Medicine Service, Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari, University of Bari "Aldo Moro", and Struttura Regionale Coordinamento Puglia, Bari, Italy.
Lazzaro di MauroImmunohematology and Transfusion Medicine Service, Fondazione IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo, Italy.
Mario MastroiannoScientific Direction, Fondazione IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo, Italy.
Nadia CoffettiImmunohematology and Transfusion Medicine Service, A.S.S.T. Bergamo Est, Seriate, Bergamo, Italy.
Roberto DovigoImmunohematology and Transfusion Medicine Service, A.S.S.T. Bergamo Est, Seriate, Bergamo, Italy.
Giovanna MeneghiniTransfusion Medicine Service, Area Vasta 5, Ascoli Piceno-San Benedetto del Tronto, Italy.
Anna TurriniLaboratorio Analisi Chimico-Cliniche e di Medicina Trasfusionale, Ospedale "Sacro Cuore-Don Calabria", Negrar, Verona, Italy.
Giobatta CavalleroDepartment of Internal Medicine, "Santa Croce e Carle" Hospital, Cuneo, Italy.
Filomena CappucciThrombosis and Haemostasis Unit, Fondazione IRCCS "Casa Sollievo della Sofferenza", Viale Cappuccini, 71013, San Giovanni Rotondo, Italy.
Patrizia VerguraThrombosis and Haemostasis Unit, Fondazione IRCCS "Casa Sollievo della Sofferenza", Viale Cappuccini, 71013, San Giovanni Rotondo, Italy.
Antonio De LaurenzoThrombosis and Haemostasis Unit, Fondazione IRCCS "Casa Sollievo della Sofferenza", Viale Cappuccini, 71013, San Giovanni Rotondo, Italy.
Alberto TosettoHaematology Department, San Bortolo Hospital, Vicenza, Italy.
Maurizio MargaglioneMedical Genetics, University of Foggia, Foggia, Italy.
FCSA (Italian Federation of Anticoagulation Clinics)
Casa Sollievo della Sofferenza · ITUniversity of Bergamo · ITAzienda Sanitaria Ospedaliera S.Croce e Carle Cuneo · ITAzienda Universitaria Ospedaliera Consorziale - Policlinico Bari · ITOspedale Sacro Cuore Don Calabria · ITOspedale San Bortolo · ITSechenov University · RUUniversity of Foggia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Knowledge of the distribution of risk factors for superficial thrombosis (SVT) in low-risk population is fundamental to improve the prevention of the disease in each individual and high-risk settings of patients. Exact frequency data for the low-risk population are scarce, but could be useful for optimal use of prophylactic strategies against venous thrombosis. Blood donors represent a low-risk population, because are healthier than the general population. The objective of this study was to assess the prevalence of vein thrombosis, particularly SVT, and associated risk factors in a low-risk population such as blood donors. In this multicentre cross-sectional study, donors from six Italian blood banks responded to a self-administered questionnaire. The enrolment lasted from 1st June 2017 to 30th July 2018. History of vein thrombosis was referred by 89 (0.76%) individuals, (49 men) with an age-dependent effect. The prevalence reached 2.9% in women and 0.8% in men aged ≥ 49 years, with a significant difference only for women. After controlling for potential confounders, a significant and independent association was found between a history of vein thrombosis and age (OR: 1.03, 95%CI 1.01-1.05), varicose veins (OR: 15.8, 95%CI 7.7-32.6), plaster cast/bed rest (OR: 2.3, 95% CI 1.0-5.3) and transfusion (OR: 5.1, 95% CI 1.3-19.5). This study shows that low-risk individuals share the same risk factors for SVT as patients in secondary care. It also suggests that transfusion confers an increased risk of SVT in healthy population.

Indexed as

Blood DonorsAdultBlood BanksCross-Sectional StudiesFemaleHumansItalyMaleMiddle AgedPrevalenceRisk FactorsVenous ThrombosisAnticoagulationBlood donorsRisk factorsSuperficial vein thrombosis

Identifiers

PMID32436011
OpenAlexW3028257475

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.