ArticleInternational orthopaedics2020
Usefulness of inflammatory markers and clinical manifestation for an earlier method to diagnosis surgical site infection after spinal surgery.
Article in International orthopaedics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 28 citations in OpenAlex.
- Impact of thoracoscopic segmental lung resection versus wedge on early post-operative recovery and short-term prognosis in elderly patients with early non-small cell lung cancer: A retrospective non-randomised controlled cohort study.Journal of minimal access surgery · 2026Article
- C-arm-guided percutaneous biopsy combined with mNGS: a dual-modality strategy for optimizing diagnosis and targeted management of spinal infections.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Review
- Postoperative laboratory markers as predictors of early spinal surgical site infections: A retrospective cohort study.Chinese journal of traumatology = Zhonghua chuang shang za zhi · 2025Article
- Correlation of Preoperative Inflammation/Immunity Markers With Postoperative Urinary Tract Infections in Elderly Hip Fracture Patients.Orthopaedic surgery · 2025Article
- Diagnosis and management of infections related to spinal pain interventions.Anesthesia and pain medicine · 2024Review
- Meta-lasso: new insight on infection prediction after minimally invasive surgery.Medical & biological engineering & computing · 2024Article
- A prospective study to identify preoperative serum parameters for spinal implant infection detected by sonication fluid culture.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023Article
- The Inflammatory Biomarkers Behavior Profile of Patients Following Elective Degenerative Spine Surgery and Differences Compared to Those Coursing With a Postoperative Spinal Infection: Protocol for a Systematic Review.JMIR research protocols · 2023Article
- Global research characteristics and trends of infection after spinal implant surgery: a bibliometric analysis.Annals of translational medicine · 2023Article
- The detection and prediction of surgical site infections using multi-modal sensors and machine learning: Results in an animal model.Frontiers in medical technology · 2023Article
- No more tears from surgical site infections in interventional pain management.The Korean journal of pain · 2023Review
- Serum Procalcitonin Levels in Postoperative Monitoring of Diabetic Patients with Posterior Lumber Vertebral Stabilization Surgery: A Prospective Comparative Study.Turkish journal of anaesthesiology and reanimation · 2022Article
- Difference between the blood samples of patients with bone and joint tuberculosis and patients with tuberculosis studied using machine learning.Frontiers in surgery · 2022Article
- [Management of suspected early infection after osteosynthesis].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021Article
- High platelet-to-lymphocyte ratio predicts poor survival of elderly patients with hip fracture.International orthopaedics · 2021Article
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo put forward a method for earlier diagnosis of surgical site infection (SSI) after spinal surgery and identify the best cut-offs of the selective signs.
methodsNinety cases were prospectively collected in consecutive patients who underwent spinal surgery. The patients were divided into the SSI group and the normal group. White blood cell (WBC) count, lymphocyte count, serum amyloid A (SAA), procalcitonin (PCT) and C-reactive protein (CRP) were collected pre-operatively and at three andsix days post-operatively. Erythrocyte sedimentation rates (ESR) were acquired pre-operatively and at six days post-operatively. Body temperature (BT) was measured every day during hospitalisation. The conditions of the surgical sites were recorded at three and six days post-operatively. Differences of BT, the conditions of the wound and the values of the inflammatory markers between the two groups were studied. Finally, we used the receiver operating characteristic curve (ROC curve) to determine the best cut-offs of the selected signs.
resultsOf the 90 patients, SSI occurred in seven and five of them reached a definite diagnosis of SSI as their bacterial cultures were positive. Significant differences were found in CRP levels at three and six days post-operatively with a cut-off of > 59.4 mg/L and > 34.9 mg/L, respectively; ESR level at six days post-operatively with a cut-off of > 51.5 mm/h; PCT at three days post-operatively with a cut-off of > 0.11 ng/mL; and BT at three days post-operatively with a cut-off of > 37 °C. Also, examination of the wound is also an important sign of SSI.
conclusionCRP, ESR and PCT are considered useful markers for earlier diagnosis of SSI. Combining the above markers with BT and the wound condition yields more accurate results.
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