Evidence map›Paper›PMID 32435816›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2020

To Interpret the SARS-CoV-2 Test, Consider the Cycle Threshold Value.

Michael R Tom, Michael J Mina

2 registry-linked trialsAbstract readComment
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 225 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
225citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05525832 nacompletednot on this mapstarted 2021, after this paper: background citation

Effect of Nasopharyngeal Wash With Normal Saline on SARS-CoV2 Viral Load: A Randomized Controlled Trial

TypeinterventionalSponsorLarissa University HospitalRan2021 to 2021Enrolled50ConditionsSARS-CoV2 InfectionArmsNormal saline
NCT05618483 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Clinical Efficacy of Xylitol Based Nasal Spray for the Treatment of Mild COVID-19 Infection

TypeinterventionalSponsorXlear, IncRan2022 to 2024Enrolled80ConditionsRespiratory Viral InfectionArmsNasal Spray
3 · Its place in the literature

Who cites it

225 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  4. COVID-19 prophylaxis with doxycycline and zinc in health care workers: a prospective, randomized, double-blind clinical trial.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2022
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165 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Michael R TomHarvard-MIT Division of Health Sciences and Technology, Harvard Medical School, Boston, Massachusetts, USA.
Michael J MinaCenter for Communicable Disease Dynamics, Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.

Funding

Deconvolution and reconstruction of immune histories to enhance infectious disease prevention and vaccination strategies and optimize surveillance effortsDP5OD028145 · OD · HARVARD SCHOOL OF PUBLIC HEALTH · PI HOFMAN, ALBERT · 2019 to 2021
$1.2M
NIH HHS DP5 OD028145
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BetacoronavirusCoronavirus InfectionsPandemicsPneumonia, ViralClinical Laboratory TechniquesCOVID-19COVID-19 TestingHumansReverse Transcriptase Polymerase Chain ReactionSARS-CoV-2COVID-19RT-PCRSARS-CoV-2testviral shedding

Identifiers

PMID32435816
PMCPMC7314112

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.