ArticleInflammatory bowel diseases2021
Responsiveness of the Patient-reported Outcomes Measurement Information System (PROMIS) Pediatric Measures to Changes in Disease Status and Quality of Life Among Children and Adolescents With Crohn's Disease.
Article in Inflammatory bowel diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Use of Patient-Reported Outcomes Measurement Information System Pediatric Measures as Clinical Trial Endpoints: Experience from a Multicenter Pragmatic Trial in Children with Crohn's Disease.The Journal of pediatrics · 2022Trial
- Health Mindset in Pediatric Inflammatory Bowel Disease: Exploring the Relationship Between Health Mindset and Key Physical and Psychosocial Outcomes.Children (Basel, Switzerland) · 2026Article
- Fatigue in inflammatory bowel disease: Prevalence, risk factors, assessment, outcomes, and management.World journal of gastrointestinal pathophysiology · 2025Review
- Implementing routine medical and mental health screening in children and adolescents with inflammatory bowel disease.Journal of pediatric gastroenterology and nutrition · 2025Article
- Discrepancies in perceptions of well-being: comparing parental and pediatric PROMIS-patient-reported outcomes in Crohn's disease.Journal of patient-reported outcomes · 2025Article
- Clinical usefulness of patient-reported-outcome-measurement information system in Pediatric Crohn's Disease: a cross-sectional study.Health and quality of life outcomes · 2024Article
- Patient-Reported Outcomes Measurement Information System as a Clinical Tool for Capturing the Patient Perspective in Pediatric Inflammatory Bowel Disease: A Narrative Review.Children (Basel, Switzerland) · 2024Review
- PROMIS fatigue scores are moderately correlated with heart failure severity in pediatrics.JHLT open · 2024Article
- Responsiveness and clinical utility of PROMIS instruments in pediatric Crohn's disease: insights from a longitudinal study.Frontiers in pediatrics · 2024Article
- Health-Related Quality of Life and Perceived Stigma in Eosinophilic Esophagitis: A Real-World, US, Web-Based Survey.Gastro hep advances · 2024Article
- Transcutaneous auricular vagus nerve stimulation attenuates inflammatory bowel disease in children: a proof-of-concept clinical trial.Bioelectronic medicine · 2023Article
- The Real-World Global Use of Patient-Reported Outcomes for the Care of Patients With Inflammatory Bowel Disease.Crohn's & colitis 360 · 2023Article
- Computerized-adaptive testing versus short forms for pediatric inflammatory bowel disease patient-reported outcome assessment.Journal of clinical and translational science · 2023Article
- Self-Reported Health Outcomes of Children and Youth with 10 Chronic Diseases.The Journal of pediatrics · 2022Article
- Anxiety and Depressive Symptoms Are Not Associated With Future Pediatric Crohn's Disease Activity.Inflammatory bowel diseases · 2022Article
- Depression and Anxiety Symptoms During and After Pediatric Asthma Hospitalization.Hospital pediatrics · 2021Article
- Can Steps per Day Reflect Symptoms in Children and Adolescents Undergoing Cancer Treatment?Cancer nursingArticle
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8 authors.
Funding
Abstract
backgroundPROMIS Pediatric domains provide self-reported measures of physical, emotional, and social health in children with chronic conditions. We evaluated the responsiveness of the PROMIS Pediatric measures to changes in disease activity and disease-specific, health-related quality of life (HRQOL) in children with Crohn's disease (CD).
methodsIBD Partners Kids & Teens is an internet-based cohort of children with inflammatory bowel disease (IBD). Participants age 9 to 17 report symptoms related to disease activity (short Crohn's Disease Activity Index [sCDAI]), the IMPACT-III HRQOL measure, and 5 PROMIS Pediatric domains. We conducted longitudinal analyses using mixed linear models to examine the extent to which PROMIS Pediatric measures respond to changes in sCDAI and IMPACT-III.
resultsOur study sample included 544 participants with CD (mean age 13 years, 44% female). All PROMIS Pediatric domains responded to changes in sCDAI, indicating improved physical, emotional, and social health, corresponding to improved disease activity and the converse (P < 0.001). Observed effect estimates ranged from 1.8 for peer relationships to 6.8 for fatigue. Of 246 participants with 2 or more completed reports, disease activity was stable in 527, worse in 72, and improved in 67. Changes in PROMIS Pediatric scores were associated with changes in IMPACT-III (r = -0.43 for anxiety, r = -0.45 for depressive symptoms, r = -0.43 for pain interference, r = -0.59 for fatigue, and r = 0.23 for peer relationships).
conclusionsThis study provides evidence for the longitudinal responsiveness of the PROMIS Pediatric measures to change in disease status and HRQOL in pediatric CD patients.
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