ArticlePersonality neuroscience2019
Openness to experience predicts dopamine effects on divergent thinking.
Article in Personality neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 33 citations in OpenAlex.
- Are Adolescents with Higher Openness More Creative Under Stress? The Mediating Role of Stress Perception and Cognitive Flexibility.Journal of Intelligence · 2026Article
- Dopaminergic and Noradrenergic Contributions to Divergent and Convergent Creativity Task Performance, a Systematic Review.Behavioral sciences (Basel, Switzerland) · 2025Review
- The 7 Muses of Neuro-Creative Cycle: How some patients with Parkinson's disease can unleash latent creativity.AIMS neuroscience · 2025Article
- Conceptualizing a less paranoid schizophrenia.Philosophy, ethics, and humanities in medicine : PEHM · 2023Review
- Openness and age influence cognitive progression: a longitudinal study.Arquivos de neuro-psiquiatria · 2023Article
- Direct and indirect effects of self-directed learning on creativity in healthcare undergraduates: a chain mediation model of openness to challenge and diversity and creative self-efficacy.Frontiers in psychology · 2023Article
- Editorial: an emerging field with bright prospects.Personality neuroscience · 2023Article
- Reward enhances connectivity between the ventral striatum and the default mode network.NeuroImage · 2022Article
- Does openness/intellect predict sensitivity to the reward value of information?Cognitive, affective & behavioral neuroscience · 2021Article
- A low dosage of the dopamine D2-receptor antagonist sulpiride affects effort allocation for reward regardless of trait extraversion.Personality neuroscience · 2020Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Individual differences in trait levels of openness to experience and creativity have been theoretically linked to dopamine function. However, empirical evidence for this assumption is scarce, especially for causal connections. The present study aims to directly assess the influence of dopamine activity on the established association between openness to experience and divergent thinking (i.e., an index of creativity). We hypothesized that manipulating dopamine activity alters the relationship between self-reported openness to experience and ideational fluency and flexibility. In a placebo-controlled between-subjects design, 193 healthy male volunteers completed four divergent thinking tasks after they received either the dopamine-receptor blocker sulpiride (200 mg) or a placebo. The data revealed an interaction such that openness to experience was more positively associated with divergent thinking in the dopamine blocker group (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.