ArticleNeurobiology of stress2020
Allopregnanolone in premenstrual dysphoric disorder (PMDD): Evidence for dysregulated sensitivity to GABA-A receptor modulating neuroactive steroids across the menstrual cycle.
Article in Neurobiology of stress, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02777372 (Psychophysiology, Neurosteroids, and Stress in Premenstrual Dysphoric Disorder), which is not on this map. Cited by 82 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Psychophysiology, Neurosteroids, and Stress in Premenstrual Dysphoric Disorder
Who cites it
82 citing papers in PubMed, 5 syntheses or guidelines pooled it, 177 citations in OpenAlex.
- Functional MRI evidence of brain alterations in premenstrual dysphoric disorder: a systematic review.Frontiers in psychiatry · 2026Pooled it
- The prevalence of traumatic exposure in women with premenstrual dysphoric disorder (PMDD): a systematic review.Archives of women's mental health · 2025Pooled it
- Intermittent selective serotonin reuptake inhibitors for premenstrual syndromes: A systematic review and meta-analysis of randomised trials.Journal of psychopharmacology (Oxford, England) · 2023Pooled it
- Cys-loop receptors on cannabinoids: All high?Frontiers in physiology · 2022Pooled it
- Association Between Smoking and Premenstrual Syndrome: A Meta-Analysis.Frontiers in psychiatry · 2020Pooled it
- Effects of estrogen and progesterone on neuroactive steroids and cytokines in patients with suicidality.Psychoneuroendocrinology · 2023Trial
- New Pharmacological Approaches to the Management of Premenstrual Dysphoric Disorder.CNS drugs · 2023Trial
- Effects of oral contraceptive pills on mood and magnetic resonance imaging measures of prefrontal cortical thickness.Molecular psychiatry · 2021Trial
- A study of changes in insulin requirements related to the menstrual cycle in Japanese women with type 1 diabetes using the advanced hybrid closed-loop system.Journal of diabetes investigation · 2026Article
- Premenstrual Disorders in Adolescents: An Interdisciplinary Perspective.Journal of clinical medicine · 2026Review
- Article
- A Genome-Wide Association Study of Premenstrual Symptoms in Two Nordic Populations.Biological psychiatry global open science · 2026Article
- Associations Between Different Subtypes of Adverse Childhood Experiences with Reproductive Mood Disorders-a Scoping Review.Current psychiatry reports · 2026Article
- Article
- Advances in Perinatal Depression: A Focus on Screening and Treatment.Journal of clinical medicine · 2026Review
- Advancing women's mental health: Recommendations from a National Academies of Sciences, Engineering, and Medicine workshop.PNAS nexus · 2026Article
- Molecular Mechanisms of Menstrual Cycle-Related Suicide Risk: A Selective Review of Promising Candidate Systems.Biological psychiatry · 2026Review
- A case control study of subjective sleep characteristics and polycystic ovary syndrome.Scientific reports · 2026Article
- "Every Woman Has a Different Cycle and Feels Differently": A Qualitative Study of Athlete-Centred Perspectives on Menstrual Cycle Symptoms and Management in Female Endurance Sports.Sports (Basel, Switzerland) · 2026Article
- Ovarian hormones, hormonal contraceptives and reward processing.BJPsych advances · 2026Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Premenstrual dysphoric disorder (PMDD) is a severe mood disorder with core symptoms (affective lability, irritability, depressed mood, anxiety) and increased sensitivity to stress occurring in the luteal phase of the menstrual cycle. PMDD can be conceptualized as a disorder of suboptimal sensitivity to neuroactive steroid hormones (NASs). In this review, we describe the role of the NAS allopregnanolone (ALLO), a positive allosteric modulator of the GABA
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.