ReviewTherapeutic advances in psychopharmacology2020
Psychedelic treatment of functional neurological disorder: a systematic review.
Review in Therapeutic advances in psychopharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- (Es)ketamine in functional neurological disorder: a systematic review.Frontiers in psychiatry · 2026Pooled it
- Impact of Psilocybin on Motor Function in Healthy Participants: A Phase 1, Randomised, Triple-Blind, Dose-Finding Study.CNS drugs · 2026Trial
- [Simultaneous determination of three tryptamines in foods by ultra performance liquid chromatography-tandem mass spectrometry coupled with hydrophilic column separation].Se pu = Chinese journal of chromatography · 2026Article
- Psilocybin-assisted physiotherapy for refractory motor functional neurological disorder: protocol for a randomised dose-comparison pilot study.Acta neuropsychiatrica · 2025Article
- Psychedelics in the Treatment of Neurologic and Psychiatric Disorders: Coincidence or a New Point of View.Molecular neurobiology · 2025Review
- Functional neurological disorder: Practical management.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Review
- The Role of Music in Psychedelic-Assisted Therapy: A Comparative Analysis of Neuroscientific Research, Indigenous Entheogenic Ritual, and Contemporary Care Models.Psychedelic medicine (New Rochelle, N.Y.) · 2024Article
- Traditional Indigenous-Amazonian Therapy Involving Ceremonial Tobacco Drinking as Medicine: A Transdisciplinary Multi-Epistemic Observational Study.Health education & behavior : the official publication of the Society for Public Health Education · 2024Observational
- Exploring psychedelic-assisted therapy in the treatment of functional seizures: A review of underlying mechanisms and associated brain networks.Journal of psychopharmacology (Oxford, England) · 2024Review
- Evidence versus expectancy: the development of psilocybin therapy.BJPsych bulletin · 2024Article
- Psilocybin and Motor Function: A Triple-Blind, Dose-Finding Study in Healthy Participants.Psychiatric research and clinical practice · 2024Article
- Investigation of self-treatment with lysergic acid diethylamide and psilocybin mushrooms: Findings from the Global Drug Survey 2020.Journal of psychopharmacology (Oxford, England) · 2023Article
- Psychedelics, epilepsy, and seizures: a review.Frontiers in pharmacology · 2023Review
- Potential Treatment for Obsessive-Compulsive Disorder.ACS medicinal chemistry letters · 2022Article
- Postpartum depression: A role for psychedelics?Journal of psychopharmacology (Oxford, England) · 2022Review
- Updates in Functional Movement Disorders: from Pathophysiology to Treatment Advances.Current neurology and neuroscience reports · 2022Review
- Does Psychedelic Therapy Have a Transdiagnostic Action and Prophylactic Potential?Frontiers in psychiatry · 2021Article
- Psychedelic Therapy's Transdiagnostic Effects: A Research Domain Criteria (RDoC) Perspective.Frontiers in psychiatry · 2021Review
- Improvement of functional neurological disorder after administration of esketamine nasal spray: a case report.Therapeutic advances in psychopharmacology · 2021Article
- Psychedelic-assisted therapy for functional neurological disorders: A theoretical framework and review of prior reports.Pharmacology research & perspectives · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
Functional neurological disorder (FND), formerly known as conversion disorder, causes a high burden of disability and distress, and is amongst the most commonly encountered conditions in neurology clinics and neuropsychiatric services, yet the therapeutic evidence base is somewhat limited. There has been recent interest in the therapeutic potential of psychedelics such as psilocybin and lysergic acid diethylamide (LSD), and in recent studies psychedelics have shown promise in treating a range of neuropsychiatric conditions. Modification of neural circuits associated with self-representation is thought to underlie some of this effect, and as some contemporary theories of FND focus on aberrant somatic self-representation, psychedelics may therefore represent an unexplored treatment option for FND. We systematically reviewed studies involving the use of psychedelics in FND. Nine studies published between 1954 and 1967, with a total of 26 patients, were identified. Due to restriction of licencing of psychedelic drugs since this period, no modern studies were identified. In most cases, patients received a course of psychotherapy with variable adjunctive administration of psychedelics (in a combination known as 'psycholytic therapy'), with protocols varying between studies. Of those treated, 69% (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.