Evidence map›Paper›PMID 32435137›Full record

ReviewSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society2020

Nanotechnology as a tool to overcome the bariatric surgery malabsorption.

Osaid Almeanazel, Fars Alanazi, Ibrahim Alsarra, Doaa Alshora, Faiyaz Shakeel, Ahmad Almnaizel, Mohammed Alahmed, Ehab Fouad

Open access · hybridAbstract readReview
In one paragraph

Review in Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 11 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Osaid AlmeanazelKayyali Chair for Pharmaceutical Industries, Department of Pharmaceutics, King Saud University, Riyadh, Saudi Arabia.
Fars AlanaziKayyali Chair for Pharmaceutical Industries, Department of Pharmaceutics, King Saud University, Riyadh, Saudi Arabia.
Ibrahim AlsarraKayyali Chair for Pharmaceutical Industries, Department of Pharmaceutics, King Saud University, Riyadh, Saudi Arabia.
Doaa AlshoraKayyali Chair for Pharmaceutical Industries, Department of Pharmaceutics, King Saud University, Riyadh, Saudi Arabia.
Faiyaz ShakeelKayyali Chair for Pharmaceutical Industries, Department of Pharmaceutics, King Saud University, Riyadh, Saudi Arabia.
Ahmad AlmnaizelPrince Naif for Health Research Center, King Saud University, Riyadh, Saudi Arabia.
Mohammed AlahmedPrince Naif for Health Research Center, King Saud University, Riyadh, Saudi Arabia.
Ehab FouadKayyali Chair for Pharmaceutical Industries, Department of Pharmaceutics, King Saud University, Riyadh, Saudi Arabia.
King Saud University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity is a metabolic disease that affects all ages; it is considered life-threatening condition as it leads to fatal complications such as; cardiovascular diseases and diabetes. The therapeutic options include; life-style modifications, pharmacotherapy intervention, and surgical intervention. Bariatric surgery (BS) is considered as the most effective option among the others for its rapid weight loss, maintaining the lost mass, and improving the quality of life of the patients. Nevertheless, BS leads to severe changes in the bioavailability of medications, especially for chronic diseases, which may reach to limit where the patient's life endangers. Recently, pharmaceutical formulations had developed several methods to improve the drug bioavailability of drugs though the implying of nanotechnology. Nonotechnology is responsible for reducing the size of the drugs to the nano range (<1000 nm), which increase the drug surface area, dissolution, absorption, and, most importantly, the bioavailability of these drugs. It is believed that BS malabsorption and drugs bioavailability problems can be solved using nanotechnology for its advantages in overcoming BS complications.

Indexed as

AbsorptionAGB, Adjustable Gastric bandASMBS, American Society for Metabolic and Bariatric SurgeryBariatric surgeryBioavailabilityBS, Bariatric SurgeryCFR, Code of Federal RegulationsDDS, Drug Delivery SystemFDA, Food and Drug AdministrationGIT, Gastrointestinal TractGRS, Generally Recognized as SafeISCRPE, improved supercritical reverse phase evaporationJIB, Jejunoileal bypassLAG, Laparoscopic Sleeve GastrectomyMBI, Body Mass IndexMIC, Minimum Inhibitory ConcentrationNanotechnologyRYGB, Roux-en-Y gastric bypassSCF, supercritical fluidSNEDDS, selfnanoemulsifying drug delivery systemT2DM, Type 2 Diabetes MellitusVA, veteran affairsWHO, World health organization

Identifiers

PMID32435137
PMCPMC7229319
OpenAlexW3010968237

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.