Evidence map›Paper›PMID 32434942›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2020

Therapeutic CMP-Nonulosonates against Multidrug-Resistant

Sunita Gulati, Ian C Schoenhofen, Theresa Lindhout-Djukic, Melissa J Schur, Corinna S Landig, Sudeshna Saha, Lingquan Deng, Lisa A Lewis, Bo Zheng, Ajit Varki and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Anti-Virulence Therapeutic Approaches forAntibiotics (Basel, Switzerland) · 2021
    Review
  8. Article
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Sunita GulatiDivision of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, MA 01605.
Ian C SchoenhofenHuman Health Therapeutics Research Centre, National Research Council of Canada, Ottawa, Ontario K1A 0R6, Canada; ian.schoenhofen@nrc-cnrc.gc.ca sanjay.ram@umassmed.edu.
Theresa Lindhout-DjukicHuman Health Therapeutics Research Centre, National Research Council of Canada, Ottawa, Ontario K1A 0R6, Canada.
Melissa J SchurHuman Health Therapeutics Research Centre, National Research Council of Canada, Ottawa, Ontario K1A 0R6, Canada.ORCID 0000-0002-6047-1416
Corinna S LandigDepartment of Medicine, Glycobiology Research and Training Center, University of California, San Diego, La Jolla, CA 92093; and.
Sudeshna SahaDepartment of Medicine, Glycobiology Research and Training Center, University of California, San Diego, La Jolla, CA 92093; and.ORCID 0000-0002-8195-6981
Lingquan DengDepartment of Medicine, Glycobiology Research and Training Center, University of California, San Diego, La Jolla, CA 92093; and.
Lisa A LewisDivision of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, MA 01605.ORCID 0000-0001-9469-9083
Bo ZhengDivision of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, MA 01605.ORCID 0000-0002-2237-2898
Ajit VarkiDepartment of Medicine, Glycobiology Research and Training Center, University of California, San Diego, La Jolla, CA 92093; and.ORCID 0000-0002-2206-975X
Sanjay RamDivision of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, MA 01605; ian.schoenhofen@nrc-cnrc.gc.ca sanjay.ram@umassmed.edu.
University of California San Diego · USUniversity of Massachusetts Chan Medical School · USNational Research Council Canada · CA

Funding

BIOSYNTHESIS AND REGULATION OF SUBSTITUTED SIALIC ACIDSR01GM032373 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI VARKI, AJIT P · 1985 to 2022
$6.9M
Immune defenses against Neisseria gonorrhoeaeR01AI114790 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI RAM, SANJAY, RICE, PETER A. · 2015 to 2019
$3.1M
Sialic acid analogs as novel immunotherapeutics against multidrug-resistant gonorrheaR33AI119327 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI GULATI, SUNITA, RAM, SANJAY · 2017 to 2019
$1.4M
NIAID NIH HHS R01 AI114790NIAID NIH HHS R33 AI119327NIGMS NIH HHS R01 GM032373
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCell Line, TumorComplement Factor HComplement System ProteinsCytidine MonophosphateCytidine Monophosphate N-Acetylneuraminic AcidDrug Resistance, Multiple, BacterialFemaleGonorrheaHumansLipopolysaccharidesMiceMice, Inbred BALB CMice, TransgenicNeisseria gonorrhoeaeNeuraminic AcidsCMP-deaminoneuraminic acidComplement Factor HComplement System Proteinscytidine-5'-monophosphosialic acidCytidine MonophosphateCytidine Monophosphate N-Acetylneuraminic Acidlacto-N-neotetraoselipid-linked oligosaccharidesLipopolysaccharidesNeuraminic AcidsOligosaccharidesSialic AcidsSialyltransferases

Identifiers

PMID32434942
PMCPMC7321800
OpenAlexW3027967640

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.