ReviewThe Journal of neuroscience : the official journal of the Society for Neuroscience2020
Decoding Neurotransmitter Switching: The Road Forward.
Review in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Restoration of gamma-aminobutyric acid homeostasis: A novel approach to alleviating central nervous system injury-associated immunodepression syndrome.Neural regeneration research · 2026Article
- Spinal cord regeneration deploys cell-type specific developmental and non-developmental strategies to restore neuron diversity.Nature communications · 2026Article
- SynaptoTagMe, a toolkit for in vivo mapping and modulating neurotransmission at single-cell resolution.eLife · 2026Article
- The impact of seizures on REM sleep and the cholinergic pedunculopontine nucleus in a mouse model of Dravet Syndrome.bioRxiv : the preprint server for biology · 2026Article
- Priming neuronal regeneration: early adaptive mechanisms in zebrafish CNS injury.Frontiers in molecular neuroscience · 2026Review
- The grand challenge in cellular neurophysiology.Frontiers in cellular neuroscience · 2026Article
- Increased c-Fos immunoreactivity in anxiety-related brain regions following paroxetine discontinuation.Neuropharmacology · 2025Article
- Hormone-switching islet cells: parallels to transmitter-switching neurons.Frontiers in cell and developmental biology · 2025Article
- How the brain produces generalized fear.Clinical and translational medicine · 2025Article
- Neurotransmitter Switching: A Novel Mechanism for Fear Generalization.Neuroscience bulletin · 2024Article
- Dopamine signaling from ganglion cells directs layer-specific angiogenesis in the retina.Current biology : CB · 2023Article
- Article
- Developmental regulation of GABAergic gene expression in forebrain cholinergic neurons.Frontiers in neural circuits · 2023Article
- Maintenance of neurotransmitter identity by Hox proteins through a homeostatic mechanism.Nature communications · 2022Article
- A conserved transcriptional fingerprint of multi-neurotransmitter neurons necessary for social behavior.BMC genomics · 2022Article
- Co-transmitting neurons in the lateral septal nucleus exhibit features of neurotransmitter switching.IBRO neuroscience reports · 2022Article
- Alternative neural systems: What is a neuron? (Ctenophores, sponges and placozoans).Frontiers in cell and developmental biology · 2022Article
- Article
- Social Isolation: How Can the Effects on the Cholinergic System Be Isolated?Frontiers in pharmacology · 2021Review
- Multiple Origins of Neurons From Secretory Cells.Frontiers in cell and developmental biology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Neurotransmitter switching is a form of brain plasticity in which an environmental stimulus causes neurons to replace one neurotransmitter with another, often resulting in changes in behavior. This raises the possibility of applying a specific environmental stimulus to induce a switch that can enhance a desirable behavior or ameliorate symptoms of a specific pathology. For example, a stimulus inducing an increase in the number of neurons expressing dopamine could treat Parkinson's disease, or one affecting the number expressing serotonin could alleviate depression. This may already be producing successful treatment outcomes without our knowing that transmitter switching is involved, with improvement of motor function through physical activity and cure of seasonal depression with phototherapy. This review presents prospects for future investigation of neurotransmitter switching, considering opportunities and challenges for future research and describing how the investigation of transmitter switching is likely to evolve with new tools, thus reshaping our understanding of both normal brain function and mental illness.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.