Evidence map›Paper›PMID 32434779›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020

Mechanisms Underlying Long-Term Synaptic Zinc Plasticity at Mouse Dorsal Cochlear Nucleus Glutamatergic Synapses.

Nathan W Vogler, Vincent M Betti, Jacob M Goldberg, Thanos Tzounopoulos

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. ZIP-ZnT1 complexes mediate a local ZnCellular and molecular life sciences : CMLS · 2026
    Article
  5. Review
  6. Article
  7. Cortical Zinc Signaling Is Necessary for Changes in Mouse Pupil Diameter That Are Evoked by Background Sounds with Different Contrasts.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Neuromodulatory Mechanisms Underlying Contrast Gain Control in Mouse Auditory Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  17. Review
  18. Review
  19. Zinc in the Brain: Friend or Foe?International journal of molecular sciences · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Nathan W VoglerPittsburgh Hearing Research Center and Department of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261.ORCID 0000-0002-1526-3079
Vincent M BettiDepartment of Chemistry, Colgate University, Hamilton, New York 13346.ORCID 0000-0003-0124-6793
Jacob M GoldbergDepartment of Chemistry, Colgate University, Hamilton, New York 13346.ORCID 0000-0002-8004-3769
Thanos TzounopoulosPittsburgh Hearing Research Center and Department of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261 thanos@pitt.edu.ORCID 0000-0003-4583-145X
Colgate University · USUniversity of Pittsburgh · US

Funding

Cell-specific Synaptic Plasticity in the Auditory BrainstemR01DC007905 · NIDCD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TZOUNOPOULOS, THANOS · 2007 to 2021
$6.9M
Plasticity of Presynaptic Zinc Release in the Dorsal Cochlear NucleusF31DC015924 · NIDCD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI VOGLER, NATHAN · 2016 to 2018
$132k
NIDCD NIH HHS F31 DC015924NIDCD NIH HHS R01 DC007905
6 · The paper itself

Abstract

In many brain areas, such as the neocortex, limbic structures, and auditory brainstem, synaptic zinc is released from presynaptic terminals to modulate neurotransmission. As such, synaptic zinc signaling modulates sensory processing and enhances acuity for discrimination of different sensory stimuli. Whereas sensory experience causes long-term changes in synaptic zinc signaling, the mechanisms underlying this long-term synaptic zinc plasticity remain unknown. To study these mechanisms in male and female mice, we used

Indexed as

AnimalsCochlear NucleusFemaleLong-Term Synaptic DepressionMaleMiceMice, Inbred ICRReceptors, Metabotropic GlutamateSynapsesSynaptic TransmissionZincmetabotropic glutamate receptor type 1Receptors, Metabotropic GlutamateZincauditorysynaptic mechanismssynaptic plasticitysynaptic zinc

Identifiers

PMID32434779
PMCPMC7314415
OpenAlexW3026670425

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.