Evidence map›Paper›PMID 32434511›Full record

ArticleBMC health services research2020

Overactive bladder in an integrated delivery system: a longitudinal cohort study.

Jeffrey A Linder, Joel S Weissman, Harry Reyes Nieva, Stuart Lipsitz, R Sterling Haring, Julie DeAngelis, Rita M Kristy, Kevin R Loughlin

Open access · goldAbstract read
In one paragraph

Article in BMC health services research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Jeffrey A LinderDivision of General Internal Medicine and Geriatrics, Northwestern University Feinberg School of Medicine, 750 N. Lake Shore Drive, 10th Floor, Chicago, IL, 60611, USA. jlinder@northwestern.edu.ORCID http://orcid.org/0000-0003-2217-184X
Joel S WeissmanCenter for Surgery and Public Health, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Harry Reyes NievaDivision of General Internal Medicine and Primary Care, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Stuart LipsitzCenter for Surgery and Public Health, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
R Sterling HaringDepartment of Physical Medicine and Rehabilitation, Vanderbilt University Medical Center, Nashville, TN, USA.
Julie DeAngelisAstellas Pharma Global Development, Northbrook, IL, USA.
Rita M KristyAstellas Pharma Global Development, Northbrook, IL, USA.
Kevin R LoughlinDivision of Urology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Brigham and Women's Hospital · USAstellas Pharma (United States) · USNorthwestern University · USVanderbilt University Medical Center · US

Funding

Astellas Pharma US NA
6 · The paper itself

Abstract

backgroundOveractive bladder (OAB) is common and morbid. Medication and diagnosis claims may be specific, but lack sensitivity to identify patients with overactive bladder. We used an "electronic health record (EHR) phenotype" to identify cases and describe treatment choices and anticholinergic burden for OAB.

methodsWe conducted a retrospective cohort study in a large, integrated health delivery system between July 2011 and June 2012 (2-year follow-up). We examined care from primary care and specialty clinics, medication and procedure use, and anticholinergic burden for each patient.

resultsThere were 7362 patients with an EHR OAB phenotype; 50% of patients were > 65 years old, 74% were female, and 83% were white. The distribution of care included primary care physician (PCP)/specialty co-management (25% of patients); PCP care only (18%); urology only (13%); or some other combination of specialty care (33%). Only 40% of patients were prescribed at least 1 OAB medication during the study. The mean duration of prescribed medication was 1.5 months (95% confidence interval [CI], 1.4 to 1.6 months; range, < 1 month to 24 months). Independent predictors of receipt of an OAB medication included increasing age (odds ratio [OR], 1.4 for every 10 years; 95% CI, 1.4 to 1.5), women (OR, 1.6 compared with men; 95% CI, 1.4 to 1.8), diabetes (OR, 1.3; 95% CI, 1.1 to 1.5), and certain sources of care compared with PCP-only care: PCP/specialty co-management (OR, 1.8; 95% CI, 1.5 to 2.0), urology (OR, 2.2; 95% CI, 1.8 to 2.6), and multiple specialists (OR, 1.4; 95% CI, 1.2 to 1.8). Very few patients received other treatments: biofeedback (< 1%), onabotulinumtoxinA (2%), or sacral nerve stimulation (1%). Patients who received OAB medications had significantly higher anticholinergic burden than patients who did not (anticholinergic total standardized daily dose, 125 versus 46; P < .001).

conclusionsAlthough OAB is common and morbid, in a longitudinal study using an EHR OAB phenotype 40% of patients were treated with OAB medication and only briefly.

Indexed as

Delivery of Health Care, IntegratedAgedCholinergic AntagonistsElectronic Health RecordsFemaleHumansLongitudinal StudiesMaleMiddle AgedRetrospective StudiesUrinary Bladder, OveractiveCholinergic AntagonistsAnticholinergic burdenAntimuscarinicsElectronic health recordsIntegrated delivery systemMedication and procedure useOveractive bladderOveractive bladder syndromePrimary and specialty careUrgencyUrinary incontinence

Identifiers

PMID32434511
PMCPMC7238545
OpenAlexW3028137429

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.