ArticleBMC cancer2020
Insight into bladder cancer care: study protocol of a large nationwide prospective cohort study (BlaZIB).
Article in BMC cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed.
- Predicting health-related quality of life two years post-diagnosis across seven cancer types: using machine learning to identify vulnerable patients.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- The impact of treatment for muscle-invasive bladder cancer on health-related quality of life.BJU international · 2025Article
- The impact of positive surgical margins after cystectomy on oncological outcomes: a nationwide study.BJU international · 2025Article
- Development of a prediction model for clinically-relevant fatigue: a multi-cancer approach.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Prospective comparative study of quality of life in patients with bladder cancer undergoing cystectomy with ileal conduit or bladder preservation.BMJ oncology · 2024Article
- Lifestyle Advice to Patients with Bladder Cancer: A National Survey of Dutch Urologists.Bladder cancer (Amsterdam, Netherlands) · 2024Article
- Low adherence to recommended use of neoadjuvant chemotherapy for muscle-invasive bladder cancer.World journal of urology · 2023Article
- The influence of multidisciplinary team meetings on treatment decisions in advanced bladder cancer.BJU international · 2023Article
- No Association Between BCG Instillations and COVID-19 Incidence in a Dutch Non-Muscle Invasive Bladder Cancer Cohort.Bladder cancer (Amsterdam, Netherlands) · 2023Article
- Intravesical BCG in patients with non-muscle invasive bladder cancer induces trained immunity and decreases respiratory infections.Journal for immunotherapy of cancer · 2023Observational
- Validation and reliability of the Dutch version of the EORTC QLQ-BLM30 module for assessing the health-related quality of life of patients with muscle invasive bladder cancer.Health and quality of life outcomes · 2022Article
- Non-metastatic muscle-invasive bladder cancer: the role of age in receiving treatment with curative intent.BJU international · 2022Article
- Occult lymph node metastases in patients without residual muscle-invasive bladder cancer at radical cystectomy with or without neoadjuvant chemotherapy: a nationwide study of 5417 patients.World journal of urology · 2022Article
- Validation and reliability of the Dutch version of the EORTC QLQ-NMIBC24 Questionnaire Module for patients with non-muscle-invasive bladder cancer.Journal of patient-reported outcomes · 2021Article
- Quality of Life After Bladder Cancer: A Cross-sectional Survey of Patient-reported Outcomes.European urology · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundDespite the embedding of bladder cancer management in European guidelines, large variation in clinical practice exists for applied diagnostics and treatments. This variation may affect patients' outcomes including complications, disease recurrence, progression, survival, and health-related quality of life (HRQL). Lack of detailed clinical data and HRQL data hampers a comprehensive evaluation of bladder cancer care. Through prospective data registration, this study aims to provide insight in bladder cancer care in the Netherlands and to identify barriers and modulators of optimal bladder cancer care.
methodsThis study is a nationwide prospective cohort study including all patients who were newly diagnosed with high-risk non-muscle invasive bladder cancer (HR-NMIBC; Tis and/or T1, N0, M0/x) or non-metastatic muscle invasive bladder cancer (MIBC; ≥T2, N0/x-3, M0/x) in the Netherlands between November 1st 2017 and October 31st 2019. Extensive data on patient- and tumor characteristics, diagnostics, treatment and follow-up up to 2 years after diagnosis will be collected prospectively from electronic health records in the participating hospitals by data managers of the Netherlands Cancer Registry (NCR). Additionally, patients will be requested to participate in a HRQL survey shortly after diagnosis and subsequently at 6, 12 and 24 months. The HRQL survey includes six standardized questionnaires, e.g. SCQ Comorbidity score, EQ-5D-5 L, EORTC-QLQ-C30, EORTC-QLQ-BLM30, EORTC-QLQ-NMIBC24 and BCI. Variation in care and deviation from the European guidelines will be assessed through descriptive analyses and multivariable multilevel analyses. Survival analyses will be used to assess the association between variation in care and relevant outcomes such as survival. DISCUSSION: The results of this observational study will guide modifications of clinical practice and/or adaptation of guidelines and may set the agenda for new specific research questions in the management of bladder cancer.
trial registrationRetrospectively registered in the Netherlands Trial Register. Trial identification number: NL8106. Registered on October 22nd 2019.
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