Evidence map›Paper›PMID 32434489›Full record

ArticleBMC public health2020

A cross-sectional analysis of falsified, counterfeit and substandard medicines in a low-middle income country.

Daariimaa Khurelbat, Gereltuya Dorj, Bruce Sunderland, Tsetsegmaa Sanjjav, Enkhtuul Bayarsaikhan, Davaadagva Damdinjav, Gantuya Dorj, Altantuya Jigjidsuren, Oyun Lkhagvasuren, Baasandorj Erdenetsetseg

Abstract read
In one paragraph

Article in BMC public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Efficacy of Penicillin-Streptomycin Brands againstAntibiotics (Basel, Switzerland) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Daariimaa KhurelbatSchool of Pharmacy, Mongolian National University of Medical Sciences, S. Zorig street, Ulaanbaatar, Sukhbaatar District, 14210, Mongolia.
Gereltuya DorjSchool of Pharmacy, Mongolian National University of Medical Sciences, S. Zorig street, Ulaanbaatar, Sukhbaatar District, 14210, Mongolia. gereltuya@gmail.com.ORCID http://orcid.org/0000-0001-9489-6829
Bruce SunderlandSchool of Pharmacy, Curtin University of Technology, GPO Box U1987, Perth, 6845, Western Australia.
Tsetsegmaa SanjjavSchool of Pharmacy, Mongolian National University of Medical Sciences, S. Zorig street, Ulaanbaatar, Sukhbaatar District, 14210, Mongolia.
Enkhtuul BayarsaikhanSchool of Pharmacy, Mongolian National University of Medical Sciences, S. Zorig street, Ulaanbaatar, Sukhbaatar District, 14210, Mongolia.
Davaadagva DamdinjavSchool of Pharmacy, Mongolian National University of Medical Sciences, S. Zorig street, Ulaanbaatar, Sukhbaatar District, 14210, Mongolia.
Gantuya DorjSchool of Public Health, Mongolian National University of Medical Sciences, S. Zorig street, Ulaanbaatar, Sukhbaatar District, 14210, Mongolia.
Altantuya JigjidsurenAsian Development Bank, Mongolia Resident Mission, Ulaanbaatar, Sukhbaatar District, 14210, Mongolia.
Oyun LkhagvasurenAsian Development Bank, Mongolia Resident Mission, Ulaanbaatar, Sukhbaatar District, 14210, Mongolia.
Baasandorj ErdenetsetsegSchool of Pharmacy, Mongolian National University of Medical Sciences, S. Zorig street, Ulaanbaatar, Sukhbaatar District, 14210, Mongolia.

Funding

Asian Development Bank TA8967-MON
6 · The paper itself

Abstract

backgroundHigh prevalence of falsified, counterfeit and substandard medicines pose a threat to public health and treatment failure. This study aimed to investigate the quality of selected essential medicines available in Mongolia.

methodsA cross-sectional study collected essential medicines from pharmacy outlets in Mongolia, during June and July, 2017. These products were then submitted for pharmacopoeial analysis and registration status.

resultsA total of 1770 samples from 118 pharmacy entities were purchased from wholesalers in urban and rural areas. Pharmacopoeial analysis found 179 (10.1%) samples or eleven product groups were unacceptable. The prevalence of substandard locally produced medicines (n = 105, 5.9%) was higher than imported equivalents [(n = 74, 4.17%, p = 0.0001)]. Approximately one-third of all unacceptable tests were related to assay (n = 73, 30.8%) and weight variation. Of 1770 samples, 76 (4.3%) were unregistered and the prevalence of unregistered samples was 3.8% in Ulaanbaatar city and 5.8% in rural areas, respectively.

conclusionsThis study has indicated that falsified and substandard medicines are prevalent in Mongolia. Considerable effort is required by regulatory authorities, private manufacturers, as well as importers to increase the quality of essential medicines in Mongolia.

Indexed as

CommerceCounterfeit DrugsDeveloping CountriesDrugs, EssentialPharmaciesPovertySubstandard DrugsCross-Sectional StudiesHumansMongoliaCounterfeit DrugsDrugs, EssentialSubstandard DrugsEssential medicineFalsified and substandard medicinesMongoliaQuality

Identifiers

PMID32434489
PMCPMC7240934

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.