Evidence map›Paper›PMID 32434327›Full record

ArticleJournal of the American Chemical Society2020

Radical SAM Enzyme HydE Generates Adenosylated Fe(I) Intermediates En Route to the [FeFe]-Hydrogenase Catalytic H-Cluster.

Lizhi Tao, Scott A Pattenaude, Sumedh Joshi, Tadhg P Begley, Thomas B Rauchfuss, R David Britt

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
  2. Article
  3. In vitro maturation of fully active [FeFe]-hydrogenase in a defined system including the iron carrier NfuA.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Final Stages in the Biosynthesis of the [FeFe]-Hydrogenase Active Site.Angewandte Chemie (International ed. in English) · 2024
    Article
  11. A personal account on 25 years of scientific literature on [FeFe]-hydrogenase.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2023
    Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Functional Diversity of HemN-like Proteins.ACS bio & med chem Au · 2022
    Review
  17. Review
  18. Review
  19. Organometallic FeJournal of the American Chemical Society · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lizhi TaoDepartment of Chemistry, University of California at Davis, Davis, California 95616, United States.ORCID 0000-0001-9921-2297
Scott A PattenaudeSchool of Chemical Sciences, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.ORCID 0000-0002-0564-2796
Sumedh JoshiDepartment of Chemistry, Texas A&M University, College Station, Texas 77842, United States.ORCID 0000-0002-0407-2920
Tadhg P BegleyDepartment of Chemistry, Texas A&M University, College Station, Texas 77842, United States.ORCID 0000-0001-5134-2623
Thomas B RauchfussSchool of Chemical Sciences, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.ORCID 0000-0003-2547-5128
R David BrittDepartment of Chemistry, University of California at Davis, Davis, California 95616, United States.ORCID 0000-0003-0889-8436

Funding

FE-S ENSEMBLES RELATED TO HYDROGENASE ACTIVITYR01GM061153 · NIGMS · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI RAUCHFUSS, THOMAS · 2000 to 2025
$6.7M
Supplement:Spectroscopy Investigations of Metalloenzyme MechanismsR35GM126961 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI R. David Britt · 2018 to 2026
$3.7M
NIGMS NIH HHS R01 GM061153NIGMS NIH HHS R35 GM126961
6 · The paper itself

Abstract

The H-cluster of [FeFe]-hydrogenase consists of a [4Fe-4S]

Indexed as

BiocatalysisHydrogenaseIron CompoundsMolecular ConformationS-AdenosylmethionineThermotoga maritimaHydrogenaseIron CompoundsS-Adenosylmethionine

Identifiers

PMID32434327
PMCPMC7440672

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.