Evidence map›Paper›PMID 32434298›Full record

ArticleMolecules and cells2020

NSM00158 Specifically Disrupts the CtBP2-p300 Interaction to Reverse CtBP2-Mediated Transrepression and Prevent the Occurrence of Nonunion.

Xun Chen, Wentao Zhang, Qian Zhang, Tao Song, Zirui Yu, Zhong Li, Ning Duan, Xiaoqian Dang

Abstract read
In one paragraph

Article in Molecules and cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xun ChenDepartment of Orthopedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710005, China.ORCID https://orcid.org/0000-0003-1374-6154
Wentao ZhangDepartment of Orthopaedics, Honghui Hospital, Xi'an Jiaotong University, Xi'an 710054, China.ORCID https://orcid.org/0000-0002-0546-6745
Qian ZhangThe Department of Surgery Room, Xi'an Daxing Hospital, Xi'an 710016, China.ORCID https://orcid.org/0000-0003-4703-1018
Tao SongDepartment of Orthopaedics, Honghui Hospital, Xi'an Jiaotong University, Xi'an 710054, China.ORCID https://orcid.org/0000-0002-1700-8039
Zirui YuDepartment of Orthopaedics, Honghui Hospital, Xi'an Jiaotong University, Xi'an 710054, China.ORCID https://orcid.org/0000-0003-1509-7848
Zhong LiDepartment of Orthopaedics, Honghui Hospital, Xi'an Jiaotong University, Xi'an 710054, China.ORCID https://orcid.org/0000-0001-6665-8321
Ning DuanDepartment of Orthopaedics, Honghui Hospital, Xi'an Jiaotong University, Xi'an 710054, China.ORCID https://orcid.org/0000-0003-3974-4683
Xiaoqian DangDepartment of Orthopedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710005, China.ORCID https://orcid.org/0000-0002-3594-6627

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carboxyl-terminal binding proteins (CtBPs) are transcription regulators that control gene expression in multiple cellular processes. Our recent findings indicated that overexpression of

Indexed as

Alcohol OxidoreductasesAnimalsCell DeathCell DifferentiationCell LineCell ProliferationCore Binding Factor Alpha 1 SubunitCo-Repressor ProteinsE1A-Associated p300 ProteinFracture HealingFractures, UnunitedGene Expression RegulationHumansMaleMice, NudeModels, BiologicalAlcohol OxidoreductasesCore Binding Factor Alpha 1 SubunitCo-Repressor ProteinsCTBP2 protein, humanE1A-Associated p300 ProteinEP300 protein, humanNADRepressor ProteinsRUNX2 protein, humanSmall Molecule Librariesatrophic nonunionCtBP2NSM00158p300Runx2

Identifiers

PMID32434298
PMCPMC7332362

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.