ArticleHealth services research2020
Failure to follow medication changes made at hospital discharge is associated with adverse events in 30 days.
Article in Health services research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
14 citing papers in PubMed, 41 citations in OpenAlex.
- Medication Regimen Complexity and Patient-Reported Adherence: A Cross-Sectional Study in Internal Medicine Outpatients.Patient preference and adherence · 2026Article
- Emergency Medicine Pharmacist Prescriptive Authority for Resolution of Outpatient Prescription Issues.Journal of the American College of Emergency Physicians open · 2025Article
- Co-design of a multifaceted intervention to improve quality handover of medicine information at discharge from hospital.BMC health services research · 2025Article
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- Article
- Patient medication management, understanding and adherence during the transition from hospital to outpatient care - a qualitative longitudinal study in polymorbid patients with type 2 diabetes.BMC health services research · 2024Article
- Co-design of an intervention to improve patient participation in discharge medication communication.International journal for quality in health care : journal of the International Society for Quality in Health Care · 2024Article
- Community health navigator-assisted transition of care from hospital to community: protocol for a randomised controlled trial.BMJ open · 2024Article
- Pharmacist-Led Follow-Up Program for Rural Patients with Acute Coronary Syndrome: The PLURAL-ACS Pilot Program.The Canadian journal of hospital pharmacy · 2024Article
- Uptake of pharmacist recommendations by patients after discharge: Implementation study of a patient-centered medicines review service.BMC geriatrics · 2023Article
- Comparing and validating medication complexity from insurance claims against electronic health records.Journal of managed care & specialty pharmacy · 2022Article
- Smart About Meds (SAM): a pilot randomized controlled trial of a mobile application to improve medication adherence following hospital discharge.JAMIA open · 2021Article
- Smart about medications (SAM): a digital solution to enhance medication management following hospital discharge.JAMIA open · 2021Article
- Failure to follow medication changes made at hospital discharge is associated with adverse events in 30 days.Health services research · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the hypothesis that nonadherence to medication changes made at hospital discharge is associated with an increased risk of adverse events in the 30 days postdischarge. STUDY
settingPatients admitted to hospitals in Montreal, Quebec, between 2014 and 2016. STUDY
designProspective cohort study. DATA COLLECTION: Nonadherence to medication changes was measured by comparing medications dispensed in the community with those prescribed at hospital discharge. Patient, health system, and drug regimen-level covariates were measured using medical services and pharmacy claims data as well as data abstracted from the patient's hospital chart. Multivariable Cox models were used to determine the association between nonadherence to medication changes and the risk of adverse events. PRINCIPAL
findingsAmong 2655 patients who met our inclusion criteria, mean age was 69.5 years (SD 14.7) and 1581 (60%) were males. Almost half of patients (n = 1161, 44%) were nonadherent to at least one medication change, and 860 (32%) were readmitted to hospital, visited the emergency department, or died in the 30 days postdischarge. Patients who were not adherent to any of their medication changes had a 35% higher risk of adverse events compared to those who were adherent to all medication changes (1.41 vs 1.27 events/100 person-days, adjusted hazard ratio: 1.35, 95% CI: 1.06-1.71).
conclusionsAlmost half of all patients were not adherent to some or all changes made to their medications at hospital discharge. Nonadherence to all changes was associated with an increased risk of adverse events. Interventions addressing barriers to adherence should be considered moving forward.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.