ArticleNature2020
Viral and host factors related to the clinical outcome of COVID-19.
2 registry-linked trialsOpen access · bronzeAbstract read
In one paragraph
Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 548 papers, 5 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
548citing papers in PubMed, 5 pooled it
23.0field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Modulation of Gut Microbiota to Enhance Health and Immunity of Vulnerable Individuals During COVID-19 Pandemic
A Phase II Study to Evaluate Oral Chlorophyllin in Hemorrhagic Cystitis Secondary to Radiation Therapy for Pelvic Malignancies
Who cites it
548 citing papers in PubMed, 5 syntheses or guidelines pooled it, 996 citations in OpenAlex.
- Comprehensive proteomics and meta-analysis of COVID-19 host response.Nature communications · 2023Pooled it
- Global prevalence of coronavirus disease 2019 reinfection: a systematic review and meta-analysis.BMC public health · 2023Pooled it
- Tissue factor links inflammation, thrombosis, and senescence in COVID-19.Scientific reports · 2022Pooled it
- Pooled it
- Interferon-induced transmembrane protein 3 gene polymorphisms are associated with COVID-19 susceptibility and severity: A meta-analysis.The Journal of infection · 2022Pooled it
- Phase 1 study of safety, pharmacokinetics, and antiviral activity of SARS-CoV-2 neutralizing monoclonal antibody ABBV-47D11 in patients with COVID-19.Pharmacology research & perspectives · 2023Trial
- A Phase 2 Trial of the Effect of Antiandrogen Therapy on COVID-19 Outcome: No Evidence of Benefit, Supported by Epidemiology and In Vitro Data.European urology · 2022Trial
- Cysteine supplementation reverses immune dysfunction in cancer patients with severe COVID-19.medRxiv : the preprint server for health sciences · 2026Article
- Cellular hallmarks and aging clock of the human lung parenchyma.Nature communications · 2026Article
- Selected Cannabinoids, Cannabimimetic Agents andPharmaceuticals (Basel, Switzerland) · 2026Review
- Platelet-to-Lymphocyte Ratio-A Real or Fake Bridge Between Inflammation and Coagulation in COVID-19 Patients: A Scoping Review.Diagnostics (Basel, Switzerland) · 2026Review
- Dual antiviral and anti-inflammatory effects of BAY 11-7082 in SARS-CoV-2 infection via inhibition of the canonical NF-κB signaling pathway.Scientific reports · 2026Article
- Clinical characteristics and risk factors associated with mortality in hospitalized patients with COVID-19 aged 90 years or older.Medicine · 2026Article
- Ischaemic heart disease is the factor associated with severe COVID-19 in the urban population of Uzbekistan: a single‑center retrospective study.BMC infectious diseases · 2026Article
- Cytokine-driven modulation of peripheral immune cell populations in Coronavirus disease 2019 patients.Frontiers in immunology · 2026Article
- Prospective observational study of cell-free DNA as a prognostic biomarker in COVID-19 and bacterial sepsis: COVSEP-study.Scientific reports · 2025Observational
- Excessive activation of JAK-STAT signaling contributes to inflammation induced by acuteVirulence · 2025Article
- Epidemiology, etiopathogenesis, immune response, diagnosis, and complications of acute pancreatitis: current insights.Annals of medicine · 2025Review
- Minimalistic transcriptomic signatures permit accurate early prediction of COVID-19 mortality.JCI insight · 2025Article
- The Way of SARS-CoV-2 Pneumonia-An Early-Pandemic Review of the Key Manifestations and Severity.Journal of clinical medicine · 2025Review
488 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
25 authors at 4 institutions in 1 country.
Xiaonan Zhang *Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0002-1286-7280
Yun Tan *National Research Center for Translational Medicine, Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, Ruijin Hospital Affiliated to Shanghai Jiao Tong University (SJTU) School of Medicine, Shanghai, China.ORCID http://orcid.org/0000-0001-8450-0392
Yun Ling *Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Gang Lu *National Research Center for Translational Medicine, Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, Ruijin Hospital Affiliated to Shanghai Jiao Tong University (SJTU) School of Medicine, Shanghai, China.
Feng Liu *National Research Center for Translational Medicine, Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, Ruijin Hospital Affiliated to Shanghai Jiao Tong University (SJTU) School of Medicine, Shanghai, China.
Zhigang Yi *Shanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Xiaofang JiaShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Min WuShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Bisheng ShiShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Shuibao XuShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Jun ChenShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Wei WangShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Bing ChenNational Research Center for Translational Medicine, Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, Ruijin Hospital Affiliated to Shanghai Jiao Tong University (SJTU) School of Medicine, Shanghai, China.
Lu JiangNational Research Center for Translational Medicine, Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, Ruijin Hospital Affiliated to Shanghai Jiao Tong University (SJTU) School of Medicine, Shanghai, China.
Shuting YuNational Research Center for Translational Medicine, Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, Ruijin Hospital Affiliated to Shanghai Jiao Tong University (SJTU) School of Medicine, Shanghai, China.
Jing LuNational Research Center for Translational Medicine, Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, Ruijin Hospital Affiliated to Shanghai Jiao Tong University (SJTU) School of Medicine, Shanghai, China.
Jinzeng WangNational Research Center for Translational Medicine, Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, Ruijin Hospital Affiliated to Shanghai Jiao Tong University (SJTU) School of Medicine, Shanghai, China.
Mingzhu XuShanghai Public Health Clinical Center, Fudan University, Shanghai, China.
Zhenghong YuanKey Laboratory of Medical Molecular Virology, Shanghai Medical College, Fudan University, Shanghai, China.
Qin ZhangTong Ren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xinxin ZhangResearch Laboratory of Clinical Virology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University (SJTU) School of Medicine, Shanghai, China.
Guoping ZhaoInstitute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
Shengyue WangNational Research Center for Translational Medicine, Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, Ruijin Hospital Affiliated to Shanghai Jiao Tong University (SJTU) School of Medicine, Shanghai, China. wsy12115@rjh.com.cn.ORCID http://orcid.org/0000-0001-9589-7719
Saijuan ChenNational Research Center for Translational Medicine, Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, Ruijin Hospital Affiliated to Shanghai Jiao Tong University (SJTU) School of Medicine, Shanghai, China. sjchen@stn.sh.cn.ORCID http://orcid.org/0000-0003-3789-1284
Hongzhou LuShanghai Public Health Clinical Center, Fudan University, Shanghai, China. luhongzhou@shphc.org.cn.ORCID http://orcid.org/0000-0002-8308-5534
Shanghai Jiao Tong University · CNShanghai Public Health Clinical Center · CNShanghai Medical College of Fudan University · CNChinese Academy of Sciences · CN
Funding
No grant is acknowledged in the PubMed record.
Abstract
In December 2019, coronavirus disease 2019 (COVID-19), which is caused by the new coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified in Wuhan (Hubei province, China)
Indexed as
AdolescentAdultAgedAged, 80 and overAgingAnimalsAsymptomatic InfectionsBetacoronavirusChinaCohort StudiesCoronavirus InfectionsCOVID-19Critical IllnessDisease ProgressionEvolution, MolecularFemaleInflammation MediatorsInterleukin-6Interleukin-8
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
NCT04884776ClinicalTrials.gov
NCT05348239ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.