Evidence map›Paper›PMID 32434159›Full record

ArticlePhysics in medicine and biology2020

A detailed Monte Carlo evaluation of

Tara Gray, Nema Bassiri, Shaquan David, Devanshi Yogeshkumar Patel, Sotirios Stathakis, Neil Kirby, Kathryn M Mayer

Abstract readComparative Study
In one paragraph

Article in Physics in medicine and biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tara GrayThe University of Texas at San Antonio, Department of Physics and Astronomy, San Antonio, TX 78249, United States of America.
Nema BassiriThe University of Texas Health Science Center at San Antonio, Department of Radiation Oncology, San Antonio, TX 78229, United States of America.
Shaquan DavidThe University of Texas at San Antonio, Department of Physics and Astronomy, San Antonio, TX 78249, United States of America.
Devanshi Yogeshkumar PatelThe University of Texas at San Antonio, Department of Physics and Astronomy, San Antonio, TX 78249, United States of America.
Sotirios StathakisThe University of Texas Health Science Center at San Antonio, Department of Radiation Oncology, San Antonio, TX 78229, United States of America.
Neil KirbyThe University of Texas Health Science Center at San Antonio, Department of Radiation Oncology, San Antonio, TX 78229, United States of America.
Kathryn M MayerThe University of Texas at San Antonio, Department of Physics and Astronomy, San Antonio, TX 78249, United States of America.ORCID 0000-0002-9533-8527

Funding

UTSA RISE Research Training ProgramR25GM060655 · NIGMS · UNIVERSITY OF TEXAS SAN ANTONIO · PI BAREA-RODRIGUEZ, EDWIN J · 2000 to 2022
$21.6M
NIGMS NIH HHS R25 GM060655
6 · The paper itself

Abstract

Gold nanoparticles (GNPs) have been studied extensively as promising radiation dose enhancing agents. In the current study, the dose enhancement effect of GNPs for Ir-192 HDR brachytherapy is studied using Monte Carlo N-Particle code, version 6.2 (MCNP6.2) and compared with experimental results obtained using Burlin cavity theory formalism. The Ir-192 source is verified using TG-43 parameters and dose enhancement factors (DEFs) from GNPs are simulated for three different mass percentages of gold in the GNP solution. These results are compared to DEFs previously reported experimentally by our group (Bassiri et al 2019 Med. Phys.) for a GNP-containing volume in an apparatus designed in-house to measure dose enhancement with GNPs for high dose rate (HDR) Ir-192 brachytherapy. An HDR Ir-192 Microselectron v2 r HDR brachytherapy source was modeled using MCNP6.2 using the TG-43 formalism in water. Anisotropy and radial dose function were verified against known values. An apparatus designed to measure dose enhancement to a 0.75 cm

Indexed as

Metal NanoparticlesMonte Carlo MethodRadiation DosageAnisotropyBrachytherapyGoldHumansIridium RadioisotopesRadiotherapy DosageWaterGoldIridium-192Iridium RadioisotopesWater

Identifiers

PMID32434159
PMCPMC7927155

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.