ArticleThe Plant journal : for cell and molecular biology2020
AKR2A interacts with KCS1 to improve VLCFAs contents and chilling tolerance of Arabidopsis thaliana.
Article in The Plant journal : for cell and molecular biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 45 citations in OpenAlex.
- AaSIZ1-Mediated SUMOylation of AaMYB31 Positively Regulates Freezing Tolerance in Actinidia arguta.Plant biotechnology journal · 2026Article
- Genome-wide analysis of the KCS gene family in Medicago truncatula and their expression profile under various abiotic stress.Scientific reports · 2025Article
- Integrative Profiling of Phytohormones, Metabolomics, and Transcriptomics Reveals Key Regulators of Cold Tolerance in Cucumber Leaves.Food science & nutrition · 2025Article
- Spatiotemporal transcriptome and metabolome landscapes of cotton fiber during initiation and early development.Nature communications · 2025Article
- Transcriptional regulation of miR528-PPO module by miR156 targeted SPLs orchestrates chilling response in banana.Molecular horticulture · 2025Article
- Arabidopsis DREB26/ERF12 and its close relatives regulate cuticular wax biosynthesis under drought stress condition.The Plant journal : for cell and molecular biology · 2024Article
- Rhythmic lipid and gene expression responses to chilling in panicoid grasses.Journal of experimental botany · 2024Article
- Identifying Core Genes Related to Low-Temperature Stress Resistance in Quinoa Seedlings Based on WGCNA.International journal of molecular sciences · 2024Article
- Comparative Transcriptome Analysis Reveals the Genes and Pathways Related to Wheat Root Hair Length.International journal of molecular sciences · 2024Article
- Comparison of transcriptome and metabolome analysis revealed cold-resistant metabolic pathways in cucumber roots under low-temperature stress in root zone.Frontiers in plant science · 2024Article
- Genome and whole-genome resequencing of Cinnamomum camphora elucidate its dominance in subtropical urban landscapes.BMC biology · 2023Article
- Apple SUMO E3 ligase MdSIZ1 regulates cuticular wax biosynthesis by SUMOylating transcription factor MdMYB30.Plant physiology · 2023Article
- Genome-wide identification and expression analysis of theFrontiers in plant science · 2023Article
- Tackling functional redundancy of Arabidopsis fatty acid elongase complexes.Frontiers in plant science · 2023Article
- AKR2A is involved in the flowering process ofPlant signaling & behavior · 2022Article
- Specific Changes inMetabolites · 2022Article
- Metabolic profiling and gene expression analyses provide insights into cold adaptation of an Antarctic mossFrontiers in plant science · 2022Article
- Correction.The Plant journal : for cell and molecular biology · 2021Article
- Review
- The ankyrin repeat-containing protein MdANK2B regulates salt tolerance and ABA sensitivity in Malus domestica.Plant cell reports · 2021Article
Corrections and comments
- Erratum issuedCorrection.2021
Authors and funding
13 authors at 4 institutions in 2 countries.
Funding
Abstract
Arabidopsis thaliana AKR2A plays an important role in plant responses to cold stress. However, its exact function in plant resistance to cold stress remains unclear. In the present study, we found that the contents of very long-chain fatty acids (VLCFAs) in akr2a mutants were decreased, and the expression level of KCS1 was also reduced. Overexpression of KCS1 in the akr2a mutants could enhance VLCFAs contents and chilling tolerance. Yeast-2-hybrid and bimolecular fluorescence complementation (BIFC) results showed that the transmembrane motif of KCS1 interacts with the PEST motif of AKR2A both in vitro and in vivo. Overexpression of KCS1 in akr2a mutants rescued akr2a mutant phenotypes, including chilling sensitivity and a decrease of VLCFAs contents. Moreover, the transgenic plants co-overexpressing AKR2A and KCS1 exhibited a greater chilling tolerance than the plants overexpressing AKR2A or KCS1 alone, as well as the wild-type. AKR2A knockdown and kcs1 knockout mutants showed the worst performance under chilling conditions. These results indicate that AKR2A is involved in chilling tolerance via an interaction with KCS1 to affect VLCFA biosynthesis in Arabidopsis.
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