Evidence map›Paper›PMID 32433809›Full record

ReviewChemistry (Weinheim an der Bergstrasse, Germany)2020

Specific Reactions of RSNO, HSNO, and HNO and Their Applications in the Design of Fluorescent Probes.

Yingying Wang, Shi Xu, Ming Xian

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Chemistry (Weinheim an der Bergstrasse, Germany), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yingying WangDepartment of Chemistry, Brown University, Providence, RI, 02912, USA.
Shi XuDepartment of Chemistry, Brown University, Providence, RI, 02912, USA.
Ming XianDepartment of Chemistry, Brown University, Providence, RI, 02912, USA.ORCID http://orcid.org/0000-0002-7902-2987

Funding

Chemical Tools for Understanding the Redox Biology of Reactive Sulfur SpeciesR01GM125968 · NIGMS · WASHINGTON STATE UNIVERSITY · PI XIAN, MING · 2018 to 2021
$1.3M
National Science Foundation CHE1954826NIGMS NIH HHS R01 GM125968NIH HHS R01GM125968
6 · The paper itself

Abstract

Nitric oxide (NO)-derived species play essential roles in regulating cellular responses. Among these species, S-nitrosothiols (including RSNO and HSNO) and nitroxyl (HNO) are especially interesting. Owing to their high reactivity and short survival time, the detection of these molecules in biological settings can be challenging. In this regard, much effort has been invested in exploring novel reactions of RSNO/HSNO/HNO and applying these reactions to develop fluorescence probes. Herein, reported specific reactions of RSNO/HSNO/HNO are summarized and strategies used in the design of fluorescent probes are illustrated. The properties and potential problems of representative probes are also discussed.

Indexed as

Fluorescent DyesNitric OxideNitrogen OxidesFluorescent DyesNitric OxideNitrogen Oxidesnitroxylfluorescent probesnitric oxideS-nitrosothiolsstructure-activity relationshipssynthesis design

Identifiers

PMID32433809
PMCPMC8211375

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.