Observational studyScientific reports2020
Anxiety and depression in diabetes care: longitudinal associations with health-related quality of life.
Observational study in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Efficacy and Safety of Agomelatine in Depressed Patients with Diabetes: A Systematic Review and Meta-Analysis.International journal of molecular sciences · 2024Pooled it
- Salivary Biomarkers Associated with Psychological Alterations in Patients with Diabetes: A Systematic Review.Medicina (Kaunas, Lithuania) · 2022Pooled it
- Blue Light Exposure During Sleep in Type 1 Diabetes: Impacts on Glycemic Control and Psychosocial Health.Journal of sleep research · 2026Trial
- Health-related quality of life in racial and ethnic minority adults with type 2 diabetes: validity and responsiveness of the EQ-5D-3L.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Trial
- How Does Hedonic Aroma Impact Long-Term Anxiety, Depression, and Quality of Life in Women with Breast Cancer? A Cross-Lagged Panel Model Analysis.International journal of environmental research and public health · 2022Trial
- The Impact of Diabetes Education by Clinical Pharmacist on Quality of Life and Treatment Satisfaction of Sudanese Individuals With Type II Diabetes Mellitus: Randomized, Double-Blind, Controlled Trial.Journal of primary care & community healthTrial
- Association Between Psychological Distress and Glycaemic Control Among Adults with Diabetes Mellitus in Saudi Arabia.Healthcare (Basel, Switzerland) · 2026Article
- Independent associations of mental health and diabetes complications with health-related quality of life: Evidence from a cross-sectional study.Diabetes, obesity & metabolism · 2026Article
- Prevalence and factors associated with comorbid depression and anxiety in patients with diabetes mellitus attending a national referral hospital in Uganda.PLOS mental health · 2026Article
- What is the cost of dedication to teaching? A school-based longitudinal quantitative study on habits and quality of life.PloS one · 2026Article
- 5. Facilitating Positive Health Behaviors and Well-being to Improve Health Outcomes: Standards of Care in Diabetes-2026.Diabetes care · 2026Review
- Quality of Life, Social Networking, and Mental Health: Generational Differentiation and Uniqueness in the Context of South Korea.Journal of clinical medicine · 2025Article
- Examining Patient Characteristics Associated With Digital Outpatient Care for Type 1 Diabetes (DigiDiaS): Cross-Sectional Study.JMIR human factors · 2025Article
- Health-related quality of life related to diabetes multisensory deficits and derealization.Scientific reports · 2025Article
- Breaking the diabetes-depression cycle: Exploring shared mechanisms, neuroinflammation, and emerging interventions for metabolic-mood comorbidities.World journal of diabetes · 2025Article
- Latent class analysis for quality of life status, sleep quality and anxiety in patients with type 2 diabetes.BMC endocrine disorders · 2025Article
- The Role of Neuroinflammation in the Comorbidity of Psychiatric Disorders and Internal Diseases.Healthcare (Basel, Switzerland) · 2025Review
- Association between Geriatric Nutrition Risk Index and depression in older hemodialysis patients with and without type 2 diabetes mellitus: a multicenter cross-sectional study.Frontiers in endocrinology · 2025Article
- Intervention strategies for type 2 diabetes prevention in high-income countries targeting low socioeconomic groups: a scoping review.Frontiers in public health · 2025Article
- 5. Facilitating Positive Health Behaviors and Well-being to Improve Health Outcomes: Standards of Care in Diabetes-2025.Diabetes care · 2025Review
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anxiety and depression are commonly found in patients with diabetes, but little is known about how the anxiety and depression symptoms of diabetes patients and the health-related quality of life (HRQoL) over time influence each other. Therefore, we conducted a survey among patients with diabetes (T1) and repeated the survey after 3 months (T2). Linear regression models and cross-lagged structural equation models were used to analyze the associations between anxiety and depression symptoms and HRQoL within and across time intervals. Correcting for baseline index and potential confounders, the HRQoL index at T2 reflected the change in anxiety/depression between T1 and T2 more than anxiety/depression at T1 (P < 0.05). Similarly, anxiety and depression at T2 reflected the change in the EQ-5D index over time more than the index at baseline (P < 0.05). Our longitudinal data fitted well in a cross-lagged model with bi-directional pathways of associations between anxiety and HRQoL, as well as depression and HRQoL, among adult patients with diabetes (x
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.