Evidence map›Paper›PMID 32432963›Full record

ArticlePharmaceutical biology2020

Protective effect of hypoxia inducible factor-1α gene therapy using recombinant adenovirus in cerebral ischaemia-reperfusion injuries in rats.

Ya-Qi Li, Zhi-Rong Hui, Tao Tao, Kang-Yu Shao, Zhi Liu, Min Li, Li-Ling Gu

Abstract read
In one paragraph

Article in Pharmaceutical biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Glucocorticoid-Dependent Mechanisms of Brain Tolerance to Hypoxia.International journal of molecular sciences · 2021
    Review
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ya-Qi LiDepartment of Emergency, Guizhou Provincial People's Hospital, Guiyang, Guizhou Province, China.
Zhi-Rong HuiDepartment of Rehabilitation Medicine, Guizhou Provincial People's Hospital, Guiyang, Guizhou Province, China.
Tao TaoDepartment of Rehabilitation Medicine, Guizhou Provincial People's Hospital, Guiyang, Guizhou Province, China.
Kang-Yu ShaoDepartment of Neurology, Chengdu Aerospace Hospital, Chengdu, Sichuan Province, China.
Zhi LiuDepartment of Pharmacy, Affiliated Hospital, Guizhou Medical University, Guiyang, Guizhou Province, China.
Min LiDepartment of Rehabilitation Medicine, Guizhou Provincial People's Hospital, Guiyang, Guizhou Province, China.
Li-Ling GuDepartment of Rehabilitation Medicine, Guizhou Provincial People's Hospital, Guiyang, Guizhou Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdenoviridaeAnimalsBrain IschemiaGenetic TherapyHypoxia-Inducible Factor 1, alpha SubunitInfusions, IntraventricularMaleNeuroprotectionRandom AllocationRatsRats, Sprague-DawleyReperfusion InjuryHif1a protein, ratHypoxia-Inducible Factor 1, alpha Subunitbrain water contentcerebral infarct volumesmodified neurological severity scoreRecombinant AdHIF-1α

Identifiers

PMID32432963
PMCPMC7301712

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.