Evidence map›Paper›PMID 32432924›Full record

ArticleAmerican journal of physiology. Cell physiology2020

Mechanisms of altered skeletal muscle action potentials in the R6/2 mouse model of Huntington's disease.

Daniel R Miranda, Eric Reed, Abdulrahman Jama, Michael Bottomley, Hongmei Ren, Mark M Rich, Andrew A Voss

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Cell physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Effects of Exercise on Skeletal Muscle Pathophysiology in Huntington's Disease.Journal of functional morphology and kinesiology · 2022
    Review
  10. Article
  11. Article
  12. Molecular Mechanisms Underlying Muscle Wasting in Huntington's Disease.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Daniel R MirandaDepartment of Biological Sciences, Wright State University, Dayton, Ohio.
Eric ReedDepartment of Biological Sciences, Wright State University, Dayton, Ohio.
Abdulrahman JamaDepartment of Biochemistry and Molecular Biology, Wright State University, Dayton, Ohio.
Michael BottomleyDepartment of Mathematics and Statistics, Wright State University, Dayton, Ohio.
Hongmei RenDepartment of Biochemistry and Molecular Biology, Wright State University, Dayton, Ohio.
Mark M RichDepartment of Neuroscience, Cell Biology, and Physiology, Wright State University, Dayton, Ohio.
Andrew A VossDepartment of Biological Sciences, Wright State University, Dayton, Ohio.ORCID 0000-0001-7530-6272
Wright State University · US

Funding

Novel Approaches to Therapy of Muscle Ion ChannelopathiesR01AR074985 · NIAMS · WRIGHT STATE UNIVERSITY · PI MARK M RICH · 2019 to 2026
$3.9M
Determining if there is a primary myopathy in Huntington's diseaseR15NS099850 · NINDS · WRIGHT STATE UNIVERSITY · PI VOSS, ANDREW ALVIN · 2018 to 2018
$455k
NIAMS NIH HHS R01 AR074985NINDS NIH HHS R15 NS099850
6 · The paper itself

Abstract

Huntington's disease (HD) patients suffer from progressive and debilitating motor dysfunction for which only palliative treatment is currently available. Previously, we discovered reduced skeletal muscle Cl

Indexed as

Disease Models, AnimalAction PotentialsAnimalsFemaleHumansHuntington DiseaseMaleMiceMice, TransgenicMuscle, Skeletalaction potentialchloride channelHuntington’s diseasepotassium channelskeletal muscle

Identifiers

PMID32432924
PMCPMC7468886
OpenAlexW3026242799

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.