Evidence map›Paper›PMID 32432402›Full record

ArticleAnnals of clinical and translational neurology2020

Longitudinal study on nerve ultrasound and corneal confocal microscopy in NF155 paranodopathy.

Diamantis Athanasopoulos, Jeremias Motte, Anna Lena Fisse, Thomas Grueter, Nadine Trampe, Dietrich Sturm, Martin Tegenthoff, Melissa Sgodzai, Rafael Klimas, Luis Querol and 2 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Annals of clinical and translational neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Clinical and Laboratory Features in Anti-NF155 Autoimmune Nodopathy.Neurology(R) neuroimmunology & neuroinflammation · 2022
    Observational
  9. Article
  10. Article
  11. Nerve Ultrasound as Helpful Tool in Polyneuropathies.Diagnostics (Basel, Switzerland) · 2021
    Review
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Diamantis AthanasopoulosDepartment of Neurology, St. Josef Hospital, Ruhr-University, Bochum, Germany.ORCID 0000-0003-3864-7523
Jeremias MotteDepartment of Neurology, St. Josef Hospital, Ruhr-University, Bochum, Germany.
Anna Lena FisseDepartment of Neurology, St. Josef Hospital, Ruhr-University, Bochum, Germany.
Thomas GrueterDepartment of Neurology, St. Josef Hospital, Ruhr-University, Bochum, Germany.
Nadine TrampeDepartment of Neurology, Katholische Kliniken Emscher-Lippe, Germany.
Dietrich SturmDepartment of Neurology, Agaplesion Bethesda Hospital, Wuppertal, Germany.
Martin TegenthoffDepartment of Neurology, Bergmannsheil University Hospital, Ruhr University, Bochum, Germany.
Melissa SgodzaiDepartment of Neurology, St. Josef Hospital, Ruhr-University, Bochum, Germany.
Rafael KlimasDepartment of Neurology, St. Josef Hospital, Ruhr-University, Bochum, Germany.
Luis QuerolUnidad de Enfermedades Neuromusculares, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Ralf GoldDepartment of Neurology, St. Josef Hospital, Ruhr-University, Bochum, Germany.
Kalliopi PitarokoiliDepartment of Neurology, St. Josef Hospital, Ruhr-University, Bochum, Germany.
St. Josef-Hospital · DEAgaplesion Bethesda Krankenhaus · DEBG University Hospital Bergmannsheil Bochum · DEHospital de Sant Pau · ESKlinikum Lippe · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of a 27-year-old patient with subacute anti-neurofascin-155 neuropathy with bifacial palsy, who showed excellent response to rituximab. We provide longitudinal data of established clinical scores, nerve conduction studies, antibody titers, and novel imaging methods (nerve ultrasonography and corneal confocal microscopy). Clinical and electrophysiological improvement followed the reduction of serum antibody titer and correlated with a reduction of corneal inflammatory cellular infiltrates whereas the increase in the cross-sectional area of the peripheral nerves remained 12 months after first manifestation. Our findings suggest that novel techniques provide useful follow-up parameters in paranodopathies.

Indexed as

AdultCell Adhesion MoleculesCorneaHumansLongitudinal StudiesMaleMicroscopy, ConfocalNerve Growth FactorsPolyradiculoneuropathy, Chronic Inflammatory DemyelinatingSpinal NervesUltrasonographyCell Adhesion MoleculesNerve Growth FactorsNFASC protein, human

Identifiers

PMID32432402
PMCPMC7318093
OpenAlexW3026714183

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.