Evidence map›Paper›PMID 32432180›Full record

ArticleTobacco prevention & cessation2017

Acute effects of short term use of ecigarettes on Airways Physiology and Respiratory Symptoms in Smokers with and without Airway Obstructive Diseases and in Healthy non smokers.

Anastasios Palamidas, Stamatoula Tsikrika, Paraskevi A Katsaounou, Sofia Vakali, Sofia-Antiopi Gennimata, George Kaltsakas, Christina Gratziou, Nikolaos Koulouris

Open access · goldAbstract read
In one paragraph

Article in Tobacco prevention & cessation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 4 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 4 syntheses or guidelines pooled it, 67 citations in OpenAlex.

  1. Pooled it
  2. Comparison of Acute Effects of E-cigarettes With and Without Nicotine and Tobacco Cigarettes on Hemodynamic and Endothelial Parameters: A Systematic Review and Meta-analysis.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2024
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  16. Oral Health of the Electronic Cigarette Smokers: A Systematic Review.Journal of pharmacy & bioallied sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Anastasios Palamidas1rst Respiratory Medicine Department, "Sotiria" General Hospital of Chest Diseases, National and Kapodistrian University of Athens.
Stamatoula Tsikrika1rst Respiratory Medicine Department, "Sotiria" General Hospital of Chest Diseases, National and Kapodistrian University of Athens.
Paraskevi A Katsaounou1rst ICU, "Evaggelismos" General Hospital, National and Kapodistrian University of Athens.
Sofia Vakali1rst Respiratory Medicine Department, "Sotiria" General Hospital of Chest Diseases, National and Kapodistrian University of Athens.
Sofia-Antiopi Gennimata1rst Respiratory Medicine Department, "Sotiria" General Hospital of Chest Diseases, National and Kapodistrian University of Athens.
George Kaltsakas1rst Respiratory Medicine Department, "Sotiria" General Hospital of Chest Diseases, National and Kapodistrian University of Athens.
Christina Gratziou1rst Respiratory Medicine Department, "Sotiria" General Hospital of Chest Diseases, National and Kapodistrian University of Athens.
Nikolaos Koulouris1rst Respiratory Medicine Department, "Sotiria" General Hospital of Chest Diseases, National and Kapodistrian University of Athens.
Sotiria General Hospital · GREvangelismos Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough the use of e-cigarettes is increasing worldwide, their short and long-term effects remain undefined. We aimed to study the acute effect of short-term use of e-cigarettes containing nicotine on lung function and respiratory symptoms in smokers with airways obstructive disease (COPD, asthma), "healthy" smokers, and healthy never smokers.

methodsRespiratory symptoms, vital signs, exhaled NO, airway temperature, airway resistance (Raw), specific airway conductance (sGaw) and single nitrogen breath test were assessed before and immediately after short term use of an e-cigarette containing 11mg of nicotine among adults with COPD, asthma, "healthy" smokers, and never-smokers. The effect of the use of nicotine-free e-cigarettes among "healthy" never smokers was also studied.

resultsThe majority of participants reported acute cough. Short term use of nicotine e-cigarettes was associated: a) with increased heart rate in all subjects except in the COPD group, b) decreased oxygen saturation in "healthy" and COPD smokers, c) increased Raw in asthmatic smokers, "healthy" smokers, and healthy never smokers, d) decreased sGaw in healthy subjects, and e) changed slope of phase III curve in asthmatic smokers. Short-term use of nicotine-free e-cigarettes increased Raw and decreased sGaw among healthy never smokers.

conclusionsShort-term use of an e-cigarette has acute effects on airways physiology and respiratory symptoms in COPD smokers, asthmatic smokers, "healthy" smokers and healthy never smokers. E-cigarette use was associated with effects in "healthy" never smokers irrespectively of nicotine concentration. More studies are needed to investigate both short and long-term effects of e-cigarette use.

Indexed as

airway inflammationairways resistanceelectronic cigaretterespiratory functionrespiratory impedance

Identifiers

PMID32432180
PMCPMC7232825
OpenAlexW2594363119

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.