ArticleFrontiers in chemistry2020
Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown
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In one paragraph
Article in Frontiers in chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 10% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.
- A bibliometric analysis on discovering anti-quorum sensing agents against clinically relevant pathogens: current status, development, and future directions.Frontiers in microbiology · 2023Pooled it
- Quorum sensing inhibition strategies for the control of Pseudomonas aeruginosa infections.World journal of microbiology & biotechnology · 2026Review
- Inhibitors of the PqsR Quorum-Sensing Receptor Reveal Differential Roles for PqsE and RhlI in Control of Phenazine Production.ACS chemical biology · 2025Article
- Discovery of Highly Potent BET Inhibitors based on a Tractable Tricyclic Scaffold.ACS medicinal chemistry letters · 2025Article
- Triblock copolymer micelles enhance solubility, permeability and activity of a quorum sensing inhibitor againstRSC applied polymers · 2024Article
- Abiotic Small Molecule Inhibitors and Activators of the LasR Quorum Sensing Receptor inACS infectious diseases · 2024Article
- Juglone as a Natural Quorum Sensing Inhibitor againstACS pharmacology & translational science · 2024Article
- In Silico and In vitro Evaluations of the Antibacterial Activities of HIV-1 Nef Peptides againstInternational journal of molecular and cellular medicine · 2024Article
- The Anti-Virulence Activities of the Antihypertensive Drug Propranolol in Light of Its Anti-Quorum Sensing Effects againstBiomedicines · 2023Article
- Development of Quinazolinone Derivatives as Modulators of Virulence Factors ofMolecules (Basel, Switzerland) · 2023Article
- Inhibition and eradication ofRSC medicinal chemistry · 2023Article
- Probing Interkingdom Signaling Molecules via Liquid Extraction Surface Analysis-Mass Spectrometry.Analytical chemistry · 2023Article
- Design of Quorum Sensing Inhibitor-Polymer Conjugates to PenetrateACS macro letters · 2023Article
- Towards Translation of PqsR Inverse Agonists: From In Vitro Efficacy Optimization to In Vivo Proof-of-Principle.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- A Comprehensive Survey of Prospective Structure-Based Virtual Screening for Early Drug Discovery in the Past Fifteen Years.International journal of molecular sciences · 2022Review
- Selectively Halogenated Flavonolignans-Preparation and Antibacterial Activity.International journal of molecular sciences · 2022Article
- Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa.Nature communications · 2022Article
- The Molecular Architecture ofMarine drugs · 2022Review
- Drug Repurposing TargetingAntibiotics (Basel, Switzerland) · 2022Article
- Quorum Sensing Inhibitors to QuenchPharmaceuticals (Basel, Switzerland) · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors at 3 institutions in 3 countries.
Fadi SoukariehSchool of Life Sciences, University of Nottingham Biodiscovery Institute, University of Nottingham, Nottingham, United Kingdom.
Ruiling LiuSchool of Pharmacy, University of Nottingham Biodiscovery Institute, University of Nottingham, Nottingham, United Kingdom.
Manuel RomeroSchool of Life Sciences, University of Nottingham Biodiscovery Institute, University of Nottingham, Nottingham, United Kingdom.
Shaun N RoberstonSchool of Life Sciences, University of Nottingham Biodiscovery Institute, University of Nottingham, Nottingham, United Kingdom.
William RichardsonSchool of Pharmacy, University of Nottingham Biodiscovery Institute, University of Nottingham, Nottingham, United Kingdom.
Simone LucantoSchool of Life Sciences, University of Nottingham Biodiscovery Institute, University of Nottingham, Nottingham, United Kingdom.
Eduard Vico OtonSchool of Life Sciences, University of Nottingham Biodiscovery Institute, University of Nottingham, Nottingham, United Kingdom.
Naim Ruhul QudusSchool of Life Sciences, University of Nottingham Biodiscovery Institute, University of Nottingham, Nottingham, United Kingdom.
Alaa MashabiSchool of Pharmacy, University of Nottingham Biodiscovery Institute, University of Nottingham, Nottingham, United Kingdom.
Scott GrossmanSchool of Pharmacy, University of Nottingham Biodiscovery Institute, University of Nottingham, Nottingham, United Kingdom.
Sadiqur AliSchool of Life Sciences, University of Nottingham Biodiscovery Institute, University of Nottingham, Nottingham, United Kingdom.
Tomás SouDrug Delivery Group, Department of Pharmacy, Uppsala University, Uppsala, Sweden.
Irena Kukavica-IbruljInstitut de Biologie Intégrative et des Systèmes, Université Laval, Quebec City, QC, Canada.
Roger C LevesqueInstitut de Biologie Intégrative et des Systèmes, Université Laval, Quebec City, QC, Canada.
Christel A S BergströmDrug Delivery Group, Department of Pharmacy, Uppsala University, Uppsala, Sweden.
Nigel HallidaySchool of Life Sciences, University of Nottingham Biodiscovery Institute, University of Nottingham, Nottingham, United Kingdom.
Shailesh N MistrySchool of Pharmacy, University of Nottingham Biodiscovery Institute, University of Nottingham, Nottingham, United Kingdom.
Jonas EmsleyThe National Biofilms Innovation Centre, University of Nottingham, Nottingham, United Kingdom.
Stephan HeebSchool of Life Sciences, University of Nottingham Biodiscovery Institute, University of Nottingham, Nottingham, United Kingdom.
Paul WilliamsSchool of Life Sciences, University of Nottingham Biodiscovery Institute, University of Nottingham, Nottingham, United Kingdom.
Miguel CámaraSchool of Life Sciences, University of Nottingham Biodiscovery Institute, University of Nottingham, Nottingham, United Kingdom.
Michael J StocksThe National Biofilms Innovation Centre, University of Nottingham, Nottingham, United Kingdom.
University of Nottingham · GBUniversité Laval · CAUppsala University · SE
Funding
Wellcome Trust
Abstract
Current treatments for
Indexed as
alkylquinolonebiofilmsMvfRPqsRPseudomonas aeruginosaPseudomonas quinolone signal (PQS)quorum quenchingquorum sensing inhibition
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.