Evidence map›Paper›PMID 32431954›Full record

ReviewBiomedical engineering letters2020

Disease diagnostics using hydrodynamic flow focusing in microfluidic devices: Beyond flow cytometry.

Aakash Rajawat, Siddhartha Tripathi

Abstract readReview
In one paragraph

Review in Biomedical engineering letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Aakash RajawatDepartment of Mechanical Engineering, Birla Institute of Technology and Science, Pilani, K. K. Birla Goa Campus, Zuarinagar, Sancoale, Goa 403726 India.
Siddhartha TripathiDepartment of Mechanical Engineering, Birla Institute of Technology and Science, Pilani, K. K. Birla Goa Campus, Zuarinagar, Sancoale, Goa 403726 India.ORCID 0000-0001-9361-3305

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The multi-disciplinary field of microfluidics has the potential to provide solutions to a diverse set of problems. It offers the advantages of high-throughput, continuous, rapid and expeditious analysis requiring minute quantities of sample. However, even as this field has yielded many mass-manufacturable and cost-efficient point-of-care devices, its direct and practical applications into the field of disease diagnostics still remain limited and largely overlooked by the industry. This review focuses on the phenomenon of hydrodynamic focusing and its potential to materialize solutions for appropriate diagnosis and prognosis. The study aims to look beyond its intended cytometric applications and focus on unambiguous disease detection, monitoring, drug delivery, studies conducted on DNA and highlight the instances in the scientific literature that have proposed such approach.

Indexed as

BloodDNADrug deliveryFlow cytometerPoint-of-care

Identifiers

PMID32431954
PMCPMC7235123

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.