Evidence map›Paper›PMID 32431868›Full record

ArticleRoyal Society open science2020

Cancer cell lines show high heritability for motility but not generation time.

Anastasia V Wass, George Butler, Tiffany B Taylor, Philip R Dash, Louise J Johnson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Royal Society open science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Anastasia V WassSchool of Biological Sciences, University of Reading, Whiteknights, Reading, Berkshire RG6 6AH, UK.
George ButlerSchool of Biological Sciences, University of Reading, Whiteknights, Reading, Berkshire RG6 6AH, UK.ORCID 0000-0002-6207-6225
Tiffany B TaylorSchool of Biological Sciences, University of Reading, Whiteknights, Reading, Berkshire RG6 6AH, UK.ORCID 0000-0002-5274-7806
Philip R DashSchool of Biological Sciences, University of Reading, Whiteknights, Reading, Berkshire RG6 6AH, UK.ORCID 0000-0002-6029-4560
Louise J JohnsonSchool of Biological Sciences, University of Reading, Whiteknights, Reading, Berkshire RG6 6AH, UK.ORCID 0000-0002-0006-1511
University of Reading · GBUniversity of Bath · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumour evolution depends on heritable differences between cells in traits affecting cell survival or replication. It is well established that cancer cells are genetically and phenotypically heterogeneous; however, the extent to which this phenotypic variation is heritable is far less well explored. Here, we estimate the broad-sense heritability (

Indexed as

cancer evolutionexperimental evolutionheritabilityphenotypic inheritance

Identifiers

PMID32431868
PMCPMC7211847
OpenAlexW3016782971

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.