ArticleAcute medicine & surgery
Association between fluid overload and delirium/coma in mechanically ventilated patients.
Article in Acute medicine & surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07438015 (VEXUS-REA), which is not on this map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
VEXUS-REA : Evaluation of Ultrasound Parameters of Venous Congestion in Patients in a Medical Intensive Care Unit
Who cites it
10 citing papers in PubMed, 11 citations in OpenAlex.
- Research advances on acute kidney injury and brain dysfunction.Frontiers in nephrology · 2026Review
- Fluid excess on intensive care unit after mechanical thrombectomy after acute ischemic stroke is associated with unfavorable neurological and functional outcomes: An observational cohort study.European stroke journal · 2025Observational
- Unsupervised machine learning analysis to identify patterns of ICU medication use for fluid overload prediction.medRxiv : the preprint server for health sciences · 2024Article
- Controlled Mechanical Ventilation in Critically Ill Patients and the Potential Role of Venous Bagging in Acute Kidney Injury.Journal of clinical medicine · 2024Article
- Perioperative Fluid Management in Colorectal Surgery: Institutional Approach to Standardized Practice.Journal of clinical medicine · 2024Review
- Machine learning vs. traditional regression analysis for fluid overload prediction in the ICU.Scientific reports · 2023Observational
- A system theory based digital model for predicting the cumulative fluid balance course in intensive care patients.Frontiers in physiology · 2023Article
- Acute kidney injury-associated delirium: a review of clinical and pathophysiological mechanisms.Critical care (London, England) · 2022Review
- Early Diuretics for De-resuscitation in Septic Patients With Left Ventricular Dysfunction.Clinical Medicine Insights. Cardiology · 2022Article
- Fluid Overload.Frontiers in veterinary science · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimSeveral studies have shown an association between fluid overload (FO) and mortality or duration of mechanical ventilation in critically ill patients. However, the association between FO and delirium duration remains unclear.
methodsThis retrospective observational cohort study was undertaken at University of Tsukuba Hospital (Tsukuba, Japan) from April 2015 to March 2017. Mechanically ventilated patients who stayed in the intensive care unit for more than 7 days were eligible for inclusion. Univariate analysis was carried out with the Mann-Whitney
resultsA total of 118 patients were included and divided into FO and non-FO groups. Fluid overload occurred in 40% of patients. The FO group had a higher APACHE II score than the non-FO group (19 [16-26] versus 23 [20-29],
conclusionsOur findings suggest that FO is associated with increased DCDs in mechanically ventilated patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.