Evidence map›Paper›PMID 32431757›Full record

ArticleJournal of smoking cessation2018

Personalized Intervention Program: Tobacco Treatment for Patients at Risk for Lung Cancer.

Krysten W Bold, Benjamin A Toll, Brenda Cartmel, Bennie B Ford, Alana M Rojewski, Ralitza Gueorguieva, Stephanie S O'Malley, Lisa M Fucito

Open access · greenAbstract read
In one paragraph

Article in Journal of smoking cessation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Effect of a Personalized Tobacco Treatment Intervention on Smoking Abstinence in Individuals Eligible for Lung Cancer Screening.Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2024
    Trial
  2. Article
  3. Article
  4. Article
  5. The worldwide burden of smoking-related oral cancer deaths.Clinical and experimental dental research · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Krysten W BoldYale School of Medicine, New Haven, CT.
Benjamin A TollYale School of Medicine, New Haven, CT.
Brenda CartmelYale School of Public Health, New Haven, CT.
Bennie B FordYale School of Medicine, New Haven, CT.
Alana M RojewskiMedical University of South Carolina, Charleston, SC.
Ralitza GueorguievaYale School of Medicine, New Haven, CT.
Stephanie S O'MalleyYale School of Medicine, New Haven, CT.
Lisa M FucitoYale School of Medicine, New Haven, CT.
Yale University · USYale Cancer Center · USMedical University of South Carolina · US

Funding

Yale SPORE in Lung Cancer (YSILC): The Biology and Personalized Treatment of Lung CancerP50CA196530 · NCI · YALE UNIVERSITY · PI Harriet M. Kluger · 2015 to 2026
$31.1M
Research Training Program in Substance Use PreventionT32DA019426 · NIDA · YALE UNIVERSITY · PI TAMI P SULLIVAN · 2005 to 2026
$7.5M
Gain-framed Messages and NRT Sampling to Promote Smoking Cessation in Lung Cancer Screening ProgramsR01CA207229 · NCI · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI TOLL, BENJAMIN ANDREW · 2016 to 2022
$3.0M
NCI NIH HHS P50 CA196530NCI NIH HHS R01 CA207229NIDA NIH HHS T32 DA019426
6 · The paper itself

Abstract

backgroundLung cancer screening and tobacco treatment for patients at high-risk for lung cancer may greatly reduce mortality from smoking, and there is an urgent need to improve smoking cessation therapies for this population.

aimsThe purpose of this study is to test the efficacy of two separate, sequential interventions to promote tobacco cessation/reduction compared to standard care in smokers considered high-risk for lung cancer.

methodsThe study will recruit 276 current smokers attending a lung cancer screening clinic or considered high-risk for lung cancer based on age and smoking history across two sites. Patients first will be randomized to either standard tobacco treatment (8 weeks of nicotine patch and five individual counselling sessions) or standard tobacco treatment plus personalized gain-framed messaging. At the 8-week visit, all patients will be re-randomized to receive biomarker feedback or no biomarker feedback. Repeated assessments during treatment will be used to evaluate changes in novel biomarkers: skin carotenoids, lung function, and plasma bilirubin that will be used for biomarker feedback. We hypothesize that personalized gain-framed messages and receiving biomarker feedback related to tobacco cessation/reduction will improve quit rates and prevent relapse compared to standard care. Primary outcomes include 7-day point-prevalence abstinence verified with expired carbon monoxide at 8 weeks and mean cigarettes per day in the past week at 6 months.

conclusionsStudy findings will inform the development of novel interventions for patients at risk for lung cancer to improve smoking cessation rates.

Identifiers

PMID32431757
PMCPMC7236885
OpenAlexW2774450243

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.