ArticleFrontiers in plant science2020
Functional Relevance of Citrulline in the Vegetative Tissues of Watermelon During Abiotic Stresses.
Article in Frontiers in plant science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 52 citations in OpenAlex.
- Chemical Composition, Biological Activities and Application ofMolecules (Basel, Switzerland) · 2026Review
- Metabolomics Analysis of Aged Garlic Extract for the Identification of Novel Compounds.Metabolites · 2026Article
- Salinity Tolerance and Antioxidant Response in Watermelon Seedlings Pre-Treated with Abiotic Stress Attenuators.Plants (Basel, Switzerland) · 2026Article
- Soil acidification dismantles a citrulline-mediated microbe-metabolite-host defense axis in watermelon, exacerbating Fusarium wilt.NPJ biofilms and microbiomes · 2026Article
- Coordinated N metabolism and NO signaling underlie allantoin-citrulline synergy in salt-stressed cucumber.BMC plant biology · 2026Article
- Genome-wide identification of the GATA transcription factor family in ten Cucurbitaceae species and expression analysis of ClGATA genes in watermelon stress responses.BMC genomics · 2026Article
- Comparative metabolomic and transcriptomic analysis revealing the role of salicylic acid for short-term response with arginine and myristic acid for long-term tolerance under salt stress in watermelon (Frontiers in plant science · 2026Article
- Effect of citrulline seed priming on growth, photosynthesis, redox equilibrium, secondary metabolic enzymes, metal sequestration and nutrient acquisition in sunflower (Helianthus annuus L.) under chromium toxicity.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2025Article
- Stress response regulation to extracellular polymeric substances biosynthesis in Bacillus licheniformis.Microbial cell factories · 2025Article
- The DIR Gene Family in Watermelon: Evolution, Stress Expression Profiles, and Functional Exploration ofInternational journal of molecular sciences · 2025Article
- Citrulline enhances salinity tolerance via photosynthesis, redox balance, osmotic and hormonal regulation, and nutrient assimilation in sunflower (Physiology and molecular biology of plants : an international journal of functional plant biology · 2025Article
- Root exudates in controlled environment agriculture: composition, function, and future directions.Frontiers in plant science · 2025Review
- Integrated transcriptomic, proteomic and metabolomic analyses revealing the roles of amino acid and sucrose metabolism in augmenting drought tolerance inFrontiers in plant science · 2024Article
- Integrated Bulk Segregant Analysis, Fine Mapping, and Transcriptome Revealed QTLs and Candidate Genes Associated with Drought Adaptation in Wild Watermelon.International journal of molecular sciences · 2023Article
- Genetic architecture of tuber-bound free amino acids in potato and effect of growing environment on the amino acid content.Scientific reports · 2023Article
- Evolutionary implications of C2 photosynthesis: how complex biochemical trade-offs may limit C4 evolution.Journal of experimental botany · 2023Article
- Article
- Genome-scale metabolic model led engineering ofFrontiers in plant science · 2023Article
- Metabolomics Combined with Transcriptomics Analysis Revealed the Amino Acids, Phenolic Acids, and Flavonol Derivatives Biosynthesis Network in DevelopingFoods (Basel, Switzerland) · 2022Article
- Differential Physio-Biochemical and Metabolic Responses of Peanut (International journal of molecular sciences · 2022Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A non-protein amino acid, citrulline, is a compatible solute involved in the maintenance of cellular osmolarity during abiotic stresses. Despite its significance, a coherent model indicating the role of citrulline during stress conditions has not yet emerged. We have used watermelon, naturally rich in citrulline, as a model to understand its accumulation during drought stress and nitrogen perturbation using transcriptomic and metabolomic analysis. Experiments were performed in the semi-controlled environment, and open field to study the accumulation of drought-induced citrulline in the vegetative tissues of watermelon by monitoring the stress treatments using physiological measurements. The amino acid profiling of leaves and stems in response to drought stress showed up to a 38 and 16-fold increase in citrulline content, respectively. Correlation between amino acids indicated a concomitant activation of a metabolic pathway that included citrulline, its precursor (ornithine), and catabolic product (arginine). Consistent with its accumulation, the gene expression analysis and RNA-Sequencing confirmed activation of citrulline biosynthesis-related genes -
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