Evidence map›Paper›PMID 32431706›Full record

ArticleFrontiers in immunology2020

Identification of a Conserved Prophenoloxidase Activation Pathway in Cotton Bollworm

Qianran Wang, Mengyi Yin, Chuanfei Yuan, Xijia Liu, Zhihong Hu, Zhen Zou, Manli Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
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  5. MicroRNA Targets PAP1 to Mediate Melanization inInternational journal of molecular sciences · 2024
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  16. Frontiers in immunology · 2022
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Qianran WangState Key Laboratory of Virology, Center for Biosafety Mega-Science, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Mengyi YinState Key Laboratory of Virology, Center for Biosafety Mega-Science, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Chuanfei YuanState Key Laboratory of Virology, Center for Biosafety Mega-Science, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Xijia LiuState Key Laboratory of Virology, Center for Biosafety Mega-Science, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Zhihong HuState Key Laboratory of Virology, Center for Biosafety Mega-Science, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Zhen ZouSavaid Medical School, University of Chinese Academy of Sciences, Beijing, China.
Manli WangState Key Laboratory of Virology, Center for Biosafety Mega-Science, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, China.
Chinese Academy of Sciences · CNInstitute of Zoology · CNWuhan Institute of Virology · CNUniversity of Chinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melanization is a prominent insect humoral response for encapsulation of and killing invading pathogens. It is mediated by a protease cascade composed of a modular serine protease (SP), and clip domain SPs (cSPs), which converts prophenoloxidase (PPO) into active phenoloxidase (PO). To date, melanization pathway in cotton bollworm

Indexed as

AnimalsCatechol OxidaseCell LineDNA Virus InfectionsDrosophilaEnzyme ActivationEnzyme PrecursorsFactor XaInsect ProteinsLepidopteraManducaNucleopolyhedrovirusesRecombinant ProteinsSignal TransductionTransfectionCatechol OxidaseEnzyme PrecursorsFactor XaInsect Proteinspro-phenoloxidaseRecombinant ProteinsbaculovirusHelicoverpa armigeramelanizationprophenoloxidaseserine protease

Identifiers

PMID32431706
PMCPMC7215089
OpenAlexW3023104408

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.