ReviewFrontiers in microbiology2020
Microalgal Metallothioneins and Phytochelatins and Their Potential Use in Bioremediation.
Review in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 1 synthesis or guideline pooled it, 181 citations in OpenAlex.
- From Metal-Related Public Health Risks to Bioremediation: The Potential of the PolyextremophilicInternational journal of molecular sciences · 2026Pooled it
- Bioactive Extracts from Yucatán Marine Invertebrates as Modulators of Microalgal Dynamics.Marine biotechnology (New York, N.Y.) · 2026Article
- Deciphering microbial approaches for heavy metal removal: an overview on their mechanisms, innovations and future horizons.Archives of microbiology · 2026Review
- Beyond carbon capture: bioengineering cyanobacteria as solar-driven platforms for remediation of recalcitrant human-generated waste.Frontiers in plant science · 2026Review
- Amine-Functionalized Maghemite Nanoflowers for Efficient Magnetic Removal of Heavy-Metal-Adsorbed Algae.International journal of molecular sciences · 2025Article
- Phyto-Algal Consortia as a Complementary System for Wastewater Treatment and Biorefinery.Plants (Basel, Switzerland) · 2025Review
- Diversity of Mercury-Tolerant Microorganisms.Microorganisms · 2025Review
- An Innovative Bioremediation Approach to Heavy Metal Removal: Combined Application ofInternational journal of molecular sciences · 2025Article
- Computational Insights into Antioxidant Enzymes and Metalloproteins ofIndian journal of microbiology · 2025Article
- The Strategies Microalgae Adopt to Counteract the Toxic Effect of Heavy Metals.Microorganisms · 2025Review
- The cadmium tolerance and bioaccumulation mechanism ofBioengineered · 2024Article
- Revolutionizing dairy waste: emerging solutions in conjunction with microbial engineering.Biodegradation · 2024Review
- Microalgae-mediated bioremediation: current trends and opportunities-a review.Archives of microbiology · 2024Review
- The MicroalgaeCells · 2024Review
- Reducing Heavy Metal Contamination in Soil and Water Using Phytoremediation.Plants (Basel, Switzerland) · 2024Review
- Microbial recovery of rare earth elements from various waste sources: a mini review with emphasis on microalgae.World journal of microbiology & biotechnology · 2024Review
- Mitigating Effect ofCells · 2024Article
- Synthesis and Biological Activities of Some Metal Complexes of Peptides: A Review.Biotech (Basel (Switzerland)) · 2024Review
- The molecular insights of cyanobacterial bioremediations of heavy metals: the current and the future challenges.Frontiers in microbiology · 2024Review
- Coupling dairy wastewaters for nutritional balancing and water recycling: sustainable heterologous 2-phenylethanol production by engineered cyanobacteria.Frontiers in bioengineering and biotechnology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The persistence of heavy metals (HMs) in the environment causes adverse effects to all living organisms; HMs accumulate along the food chain affecting different levels of biological organizations, from cells to tissues. HMs enter cells through transporter proteins and can bind to enzymes and nucleic acids interfering with their functioning. Strategies used by microalgae to minimize HM toxicity include the biosynthesis of metal-binding peptides that chelate metal cations inhibiting their activity. Metal-binding peptides include genetically encoded metallothioneins (MTs) and enzymatically produced phytochelatins (PCs). A number of techniques, including genetic engineering, focus on increasing the biosynthesis of MTs and PCs in microalgae. The present review reports the current knowledge on microalgal MTs and PCs and describes the state of art of their use for HM bioremediation and other putative biotechnological applications, also emphasizing on techniques aimed at increasing the cellular concentrations of MTs and PCs. In spite of the broad metabolic and chemical diversity of microalgae that are currently receiving increasing attention by biotechnological research, knowledge on MTs and PCs from these organisms is still limited to date.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.