Evidence map›Paper›PMID 32431658›Full record

ArticleFrontiers in neurology2020

Gait and Functional Mobility in Multiple Sclerosis: Immediate Effects of Transcranial Direct Current Stimulation (tDCS) Paired With Aerobic Exercise.

Giuseppina Pilloni, Claire Choi, Giancarlo Coghe, Eleonora Cocco, Lauren B Krupp, Massimiliano Pau, Leigh E Charvet

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05912595 (The Effects of EXOPULSE Mollii Suit on Spasticity and Muscular Oxygenation in Patients With Multiple Sclerosis.), which is not on this map. Cited by 20 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 4 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05912595 naunknown statusnot on this mapstarted 2023, after this paper: background citation

The Effects of EXOPULSE Mollii Suit on Spasticity and Muscular Oxygenation in Patients With Multiple Sclerosis.

TypeinterventionalSponsorSheikh Shakhbout Medical CityRan2023 to 2024Enrolled36ConditionsSclerosis, Multiple, MS (Multiple Sclerosis), Spastic, Spasticity, MuscleArmsEXOPULSE Mollii Suit Stimulation
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Giuseppina PilloniNYU Langone Health, Department of Neurology, New York, NY, United States.
Claire ChoiSUNY Downstate, Department of Medicine, New York, NY, United States.
Giancarlo CogheDepartment of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
Eleonora CoccoDepartment of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
Lauren B KruppNYU Langone Health, Department of Neurology, New York, NY, United States.
Massimiliano PauDepartment of Mechanical, Chemical and Materials Engineering, University of Cagliari, Cagliari, Italy.
Leigh E CharvetNYU Langone Health, Department of Neurology, New York, NY, United States.
University of Cagliari · ITNYU Langone Health · USSUNY Downstate Health Sciences University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Walking impairments are a debilitating feature of multiple sclerosis (MS) because of the direct interference with daily activity. The management of motor symptoms in those with MS remains a therapeutic challenge. Transcranial direct current stimulation (tDCS) is a type of non-invasive brain stimulation that is emerging as a promising rehabilitative tool but requires further characterization to determine its optimal therapeutic use. In this randomized, sham-controlled proof-of-concept study, we tested the immediate effects of a single tDCS session on walking and functional mobility in those with MS. Seventeen participants with MS completed one 20-min session of aerobic exercise, randomly assigned to be paired with either active (2.5 mA,

Indexed as

aerobic exercisefunctional mobilitygaitmotor rehabilitationmultiple sclerosisnon-invasive brain stimulationtDCStranscranial direct current stimulation

Identifiers

PMID32431658
PMCPMC7214839
OpenAlexW3023154928

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.