Evidence map›Paper›PMID 32431609›Full record

ArticleFrontiers in pharmacology2020

Gu-Ben-Fang-Xiao Decoction Ameliorated Murine Asthma in Remission Stage by Modulating Microbiota-Acetate-Tregs Axis.

Yingmei Dong, Hua Yan, Xia Zhao, Rui Lin, Lili Lin, Yuanyuan Ding, Liwei Liu, Lishun Ren, Qiongqiong Xing, Jianjian Ji

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Mechanisms ofBiology · 2025
    Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Yingmei DongAffiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Hua YanAffiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Xia ZhaoAffiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Rui LinJiangsu Key Laboratory of Pediatric Respiratory Disease, Institute of Pediatrics, Medical Metabolomics Center, Nanjing University of Chinese Medicine, Nanjing, China.
Lili LinAffiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Yuanyuan DingAffiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Liwei LiuThe First Affiliated Hospital of Zhejiang Chinese Medicine University, Hangzhou, China.
Lishun RenAffiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Qiongqiong XingAffiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Jianjian JiJiangsu Key Laboratory of Pediatric Respiratory Disease, Institute of Pediatrics, Medical Metabolomics Center, Nanjing University of Chinese Medicine, Nanjing, China.
Nanjing University of Chinese Medicine · CNZhejiang Chinese Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dysbiosis of gut microbiota is a critical factor in the pathogenesis of asthma. Manipulating gut microbiota is a promising therapeutic intervention in asthma, and is being extensively studied. Gu-Ben-Fang-Xiao Decoction (GBFXD), derived from traditional Chinese medicine, is an effective and safe therapeutic formula for asthma in remission stage (ARS). Herein, we showed that GBFXD treatment remarkably alleviated ARS by improving respiratory function and lung histopathology. Asthmatic mice displayed a dysbiosis of gut microbiota, represented by significantly increased abundance of

Indexed as

asthmaGu-Ben-Fang-Xiao Decoctiongut microbiotaregulatory T cellremission stageshort-chain fatty acid

Identifiers

PMID32431609
PMCPMC7212778
OpenAlexW3023053597

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.