Evidence map›Paper›PMID 32431087›Full record

Observational studyBJS open2020

Diagnostic accuracy of acute diverticulitis with unenhanced low-dose CT.

A Thorisson, M Nikberg, M R Torkzad, H Laurell, K Smedh, A Chabok

Open access · goldAbstract readComparative StudyMulticenter StudyObservational Study
In one paragraph

Observational study in BJS open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. [Diverticular disease: stage-related diagnostic imaging].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021
    Review
  11. Article
  12. Changing Paradigms in the Management of Acute Uncomplicated Diverticulitis.Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

A ThorissonDepartment of Radiology, Västerås, Sweden.ORCID 0000-0002-8499-2187
M NikbergCentre for Clinical Research Uppsala University, Västerås, Sweden.
M R TorkzadDepartment of Diagnostic Radiology, The Royal Marsden NHS Foundation Trust, Sutton, UK.
H LaurellColorectal Unit, Department of Surgery, Landstinget Dalarna, Mora, Sweden.
K SmedhCentre for Clinical Research Uppsala University, Västerås, Sweden.
A ChabokCentre for Clinical Research Uppsala University, Västerås, Sweden.
Uppsala University · SELandstinget Dalarna · SERoyal Marsden NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to evaluate the diagnostic accuracy of unenhanced low-dose CT (LDCT) in acute colonic diverticulitis in comparison with contrast-enhanced standard-dose CT (SDCT).

methodsAll patients with clinically suspected diverticulitis who underwent LDCT followed by SDCT between January and October 2017 were evaluated prospectively. CT examinations were assessed for signs of diverticulitis, complications and other differential diagnoses by three independent radiologists (two consultants and one fourth-year resident) using SDCT as the reference method. Sensitivity and specificity were calculated and Cohen's κ coefficient was used for agreement analyses.

resultsOf the 149 patients included (mean age 66·7 years, M : F ratio 0·4), 107 (71·8 per cent) had imaging consistent with diverticulitis on standard CT. Sensitivity and specificity values for a diverticulitis diagnosis using LDCT were 95-99 and 86-100 per cent respectively, and respective values for identification of complications were 58-73 and 78-100 per cent. The corresponding κ values among the three readers for diagnosis were 0·984, 0·934 and 0·816, whereas κ values for complications were 0·680, 0·703 and 0·354. Of the 26 patients who presented with other causes of abdominal symptoms identified on standard CT, 23 were diagnosed correctly on LDCT. Missed cases included splenic infarction (1) and segmental colitis (2).

conclusionThe diagnostic accuracy of LDCT was high for the presence of acute diverticulitis. However, as signs of complicated disease can be missed using the low-dose protocol, use of LDCT as a primary examination method should not preclude SDCT when complications may be suspected.

Indexed as

AgedDiverticulitisDose-Response Relationship, RadiationFemaleHumansMaleMiddle AgedProspective StudiesRadiation DosageRadiographic Image EnhancementRadiography, AbdominalReproducibility of ResultsRetrospective StudiesSensitivity and SpecificitySwedenTomography, X-Ray Computed

Identifiers

PMID32431087
PMCPMC7397358
OpenAlexW2891479246

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.