Evidence map›Paper›PMID 32430846›Full record

ReviewMolecular biology reports2020

The enzymology of the human prostanoid pathway.

Roger Gregory Biringer

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Quantifying the fidelity of in vitro human cell culture systems using a biomedical foundation model.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Molecular basis of prostaglandin ENature communications · 2025
    Article
  3. Prostaglandin DCells · 2025
    Article
  4. Review
  5. Review
  6. Structural basis of prostaglandin efflux by MRP4.Nature structural & molecular biology · 2024
    Article
  7. Review
  8. Review
  9. The Link between Prostanoids and Cardiovascular Diseases.International journal of molecular sciences · 2023
    Review
  10. Review
  11. Article
  12. Endocannabinoid signaling pathways: beyond CB1R and CB2R.Journal of cell communication and signaling · 2021
    Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Roger Gregory BiringerCollege of Osteopathic Medicine, Lake Erie College of Osteopathic Medicine, Bradenton, FL, 34211, USA. rbiringer@lecom.edu.ORCID http://orcid.org/0000-0002-9096-8343
Lake Erie College of Osteopathic Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostanoids are short-lived autocrine and paracrine signaling molecules involved in a wide range of biological functions. They have been shown to be intimately involved in many different disease states when their regulation becomes dysfunctional. In order to fully understand the progression of any disease state or the biological functions of the well state, a complete evaluation of the genomics, proteomics, and metabolomics of the system is necessary. This review is focused on the enzymology for the enzymes involved in the synthesis of the prostanoids (prostaglandins, prostacyclins and thromboxanes). In particular, the isolation and purification of the enzymes, their enzymatic parameters and catalytic mechanisms are presented.

Indexed as

HumansProstaglandinsProstaglandins ISignal TransductionThromboxanesProstaglandinsProstaglandins IThromboxanesEnzymologyKineticsProstacyclinProstaglandinProstanoidThromboxane

Identifiers

PMID32430846
OpenAlexW3027442151

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.