Evidence map›Paper›PMID 32430690›Full record

ArticleDevelopment genes and evolution2020

Expression of the zinc finger transcription factor Sp6-9 in the velvet worm Euperipatoides kanangrensis suggests a conserved role in appendage development in Panarthropoda.

Ralf Janssen, Graham E Budd

Open access · hybridAbstract read
In one paragraph

Article in Development genes and evolution, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ralf JanssenDepartment of Earth Sciences, Uppsala University, Palaeobiology, Villavägen 16, Uppsala, Sweden. ralf.janssen@geo.uu.se.ORCID 0000-0002-4026-4129
Graham E BuddDepartment of Earth Sciences, Uppsala University, Palaeobiology, Villavägen 16, Uppsala, Sweden.
Uppsala University · SE

Funding

H2020 Marie Skłodowska-Curie Actions 766053Vetenskapsrådet 621-2011-4703
6 · The paper itself

Abstract

The Sp-family genes encode important transcription factors in animal development. Here we investigate the embryonic expression patterns of the complete set of Sp-genes in the velvet worm Euperipatoides kanangrensis (Onychophora), with a special focus on the Sp6-9 ortholog. In arthropods, Sp6-9, the ortholog of the Drosophila melanogaster D-Sp1 gene plays a conserved role in appendage development. Our data show that the expression of Sp6-9 during the development of the velvet worm is conserved, suggesting that the key function of the Sp6-9 gene dates back to at least the last common ancestor of arthropods and onychophorans and thus likely the last common ancestor of Panarthropoda.

Indexed as

Amino Acid SequenceAnimalsBody PatterningEmbryonic DevelopmentEmbryo, NonmammalianGene Expression Regulation, DevelopmentalInvertebratesPhylogenySp Transcription FactorsZinc FingersSp Transcription FactorsAppendage developmentArthropod developmentButtonheadOnychophoraPanarthropodaSp1SP5

Identifiers

PMID32430690
PMCPMC7260272
OpenAlexW3026235633

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.