Evidence map›Paper›PMID 32430588›Full record

ReviewCurrent hematologic malignancy reports2020

Radiogenomics and Its Role in Lymphoma.

Saman Khan, Sohaib Naim, Rania Bilwani, Amirah Salem, David Gorlin, Ahmad Muhammad, Maryam Gul, Muhammad H Imam, Ammar Chaudhry

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current hematologic malignancy reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. BaselineEJNMMI research · 2023
    Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Saman KhanDepartment of Diagnostic Radiology, City of Hope National Cancer Center, 1500 East Duarte Road, Los Angeles, CA, 91010, USA.
Sohaib NaimDepartment of Diagnostic Radiology, City of Hope National Cancer Center, 1500 East Duarte Road, Los Angeles, CA, 91010, USA.
Rania BilwaniDepartment of Diagnostic Radiology, City of Hope National Cancer Center, 1500 East Duarte Road, Los Angeles, CA, 91010, USA.
Amirah SalemDepartment of Diagnostic Radiology, City of Hope National Cancer Center, 1500 East Duarte Road, Los Angeles, CA, 91010, USA.
David GorlinDepartment of Diagnostic Radiology, City of Hope National Cancer Center, 1500 East Duarte Road, Los Angeles, CA, 91010, USA.
Ahmad MuhammadDepartment of Diagnostic Radiology, City of Hope National Cancer Center, 1500 East Duarte Road, Los Angeles, CA, 91010, USA.
Maryam GulAmaze Research Foundation, Los Angeles, CA, USA.
Muhammad H ImamFlorida Cancer Specialists, Orlando, FL, USA.
Ammar ChaudhryDepartment of Diagnostic Radiology, City of Hope National Cancer Center, 1500 East Duarte Road, Los Angeles, CA, 91010, USA. achaudhry@coh.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewImaging features of lymphoma vary regionally. Awareness of site-specific key imaging characteristics of lymphoma can aid in rapid staging and assist in prompt treatment. FDG PET/CT and conventional MRI are readily available diagnostic modalities with excellent sensitivity and good specificity. Diagnostic specificity can be enhanced using emerging PET radiotracers, e.g., FLT and FET. RECENT

findingsEmerging research has shown higher dimensional analysis (radiomics and radiogenomics) of imaging data can yield information of the underlying genetic aberrations in lymphoma, which can aid in assessing real-time evolution of tumor. CT, PET/CT, MRI, and ultrasound accentuate the intrinsic qualities of lymphoma (e.g., FDG PET/CT for increased metabolic activity, FLT PET/CT for increased proliferation index, and DWI for increased cellularity) and play an essential role in its diagnosis and examination. Advanced radiogenomic analyses use radiomic parameters to deduce genetic variations of lymphoma, providing noninvasive, repeatable, and real-time surveillance of its genetic progression.

Indexed as

Diffusion Magnetic Resonance ImagingMolecular ImagingPositron Emission Tomography Computed TomographyBiomarkers, TumorFluorodeoxyglucose F18HumansLymphomaPredictive Value of TestsPrognosisRadiopharmaceuticalsReproducibility of ResultsBiomarkers, TumorFluorodeoxyglucose F18RadiopharmaceuticalsHodgkin’s lymphomaImaging biomarkersLymphomaNon-Hodgkin’s lymphomaRadiogenomicsRadiomics

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.