Evidence map›Paper›PMID 32430573›Full record

ArticleJournal of neurology2020

Impact of environmental factors and physical activity on disability and quality of life in CIDP.

Pietro Emiliano Doneddu, Elisa Bianchi, Dario Cocito, Fiore Manganelli, Raffaella Fazio, Massimiliano Filosto, Ettore Beghi, Anna Mazzeo, Giuseppe Cosentino, Andrea Cortese and 27 more

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Journal of neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Preventive strategies in neuroimmunology.Neurological research and practice · 2026
    Review
  2. Observational
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

37 authors at 17 institutions in 1 country.

Pietro Emiliano DonedduNeuromuscular and Neuroimmunology Service, Humanitas Clinical and Research Center-IRCCS, Rozzano, Milan, Italy.
Elisa BianchiLaboratorio di Malattie Neurologiche, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
Dario CocitoIstituti Clinici Scientifici Maugeri, Turin, Italy.
Fiore ManganelliDepartment of Neuroscience, Reproductive Sciences and Odontostomatology, University of Naples 'Federico II', Naples, Italy.
Raffaella FazioDivision of Neuroscience, Department of Neurology, Institute of Experimental Neurology (INSPE), San Raffaele Scientific Institute, Milan, Italy.
Massimiliano FilostoCenter for Neuromuscular Diseases and Neuropathies, Unit of Neurology, ASST 'Spedali Civili', University of Brescia, Brescia, Italy.
Ettore BeghiLaboratorio di Malattie Neurologiche, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
Anna MazzeoDepartment of Clinical and Experimental Medicine, Unit of Neurology, University of Messina, Messina, Italy.
Giuseppe CosentinoUniversity of Pavia, Pavia, Italy.
Andrea CorteseUniversity of Pavia, Pavia, Italy.
Stefano JannDepartment of Neuroscience, Niguarda Ca' Granda Hospital, Milan, Italy.
Angelo Maurizio ClericiNeurology Unit, Circolo and Macchi Foundation Hospital, DBSV, Insubria University, Varese, Italy.
Giovanni AntoniniDepartment of Neurology Mental Health and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, Unit of Neuromuscular Diseases, 'Sapienza' University of Rome, Sant'Andrea Hospital, Rome, Italy.
Gabriele SicilianoDepartment of Clinical and Experimental Medicine, Neurology Unit, University of Pisa, Pisa, Italy.
Girolama Alessandra MarfiaDepartment of Systems Medicine, Dysimmune Neuropathies Unit, Tor Vergata University of Rome, Rome, Italy.
Chiara BrianiDepartment of Neuroscience, Neurology Unit, University of Padua, Padua, Italy.
Giuseppe LauriaUnit of Neuroalgology, IRCCS Foundation 'Carlo Besta' Neurological Institute, Milan, Italy.
Tiziana RossoULSS2 Marca Trevigiana, UOC Neurologia-Castelfranco Veneto, Treviso, Italy.
Guido CavalettiSchool of Medicine and Surgery and Experimental Neurology Unit, University of Milano-Bicocca, Monza, Italy.
Marinella CarpoASST Bergamo Ovest-Ospedale Treviglio, Treviglio, Italy.
Luana BenedettiIRCCS Ospedale Policlinico San Martino Genova, Genoa, Italy.
Angelo SchenoneDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa and IRCCS AOU San Martino-IST, Genoa, Italy.
Giuseppe LiberatoreNeuromuscular and Neuroimmunology Service, Humanitas Clinical and Research Center-IRCCS, Rozzano, Milan, Italy.
Erdita PeciDepartment of Neuroscience, University of Turin, Turin, Italy.
Emanuele SpinaDepartment of Neuroscience, Reproductive Sciences and Odontostomatology, University of Naples 'Federico II', Naples, Italy.
Stefano TronciDivision of Neuroscience, Department of Neurology, Institute of Experimental Neurology (INSPE), San Raffaele Scientific Institute, Milan, Italy.
Stefano Cotti PiccinelliCenter for Neuromuscular Diseases and Neuropathies, Unit of Neurology, ASST 'Spedali Civili', University of Brescia, Brescia, Italy.
Antonio ToscanoDepartment of Clinical and Experimental Medicine, Unit of Neurology, University of Messina, Messina, Italy.
Luca GentileDepartment of Clinical and Experimental Medicine, Unit of Neurology, University of Messina, Messina, Italy.
Laura PiccoloUniversity of Pavia, Pavia, Italy.
Luca LeonardiDepartment of Neurology Mental Health and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, Unit of Neuromuscular Diseases, 'Sapienza' University of Rome, Sant'Andrea Hospital, Rome, Italy.
Giorgia MataluniDepartment of Systems Medicine, Dysimmune Neuropathies Unit, Tor Vergata University of Rome, Rome, Italy.
Marta RuizDepartment of Neuroscience, Neurology Unit, University of Padua, Padua, Italy.
Mario SabatelliUniversità Cattolica del Sacro Cuore. Sede di Roma, Rome, Italy.
Lucio SantoroDepartment of Neuroscience, Reproductive Sciences and Odontostomatology, University of Naples 'Federico II', Naples, Italy.
Eduardo Nobile-OrazioNeuromuscular and Neuroimmunology Service, Humanitas Clinical and Research Center-IRCCS, Rozzano, Milan, Italy. eduardo.nobile@unimi.it.
Italian CIDP Database Study Group
Humanitas University · ITUniversity of Messina · ITUniversity of Pavia · ITUniversity of Rome Tor Vergata · ITMario Negri Institute for Pharmacological Research · ITOspedale di Circolo e Fondazione Macchi · ITOspedale Policlinico San Martino · ITUniversità Cattolica del Sacro Cuore · ITUniversity of Brescia · ITUniversity of Milan · ITUniversity of Naples Federico II · ITUniversity of Pisa · ITAULSS 2 Marca Trevigiana · ITAzienda Ospedaliera Treviglio · ITIstituti Clinici Scientifici Maugeri · ITUniversity of Padua · ITUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A few observational studies and randomized trials suggest that exercise and rehabilitation may improve activity limitation and quality of life (QoL) in patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), but the impact of other modifiable factors on the severity of the disease is not well understood. Using a structured questionnaire, we collected data on lifestyle and dietary habits of the patients included in the Italian CIDP database to investigate the possible influence of modifiable lifestyle factors on disability and QoL. Questionnaire data were available for 323 patients. The effect of lifestyle and dietary exposures on impairment, disability and QoL was evaluated using logistic regression models, adjusting for age, sex, disease duration, physical activity and smoking. Physical activity was associated with lower sensory impairment by the ISS scale, less disability by the INCAT and RODS scale and a better QoL in all the domains of EURO-QoL scale with the exception of anxiety/depression. None of the other parameters had an impact on these scales. This study adds evidence to the possible role of physical activity in improving symptom severity, disability and QoL in patients with CIDP. None of the other environmental factors investigated appeared to have an impact on the severity and health perception of CIDP.

Indexed as

Persons with DisabilitiesPolyradiculoneuropathy, Chronic Inflammatory DemyelinatingExerciseHumansItalyQuality of LifeChronic inflammatory demyelinating polyradiculoneuropathyCIDPDisabilityEpidemiologyPhysical activityQuality of life

Identifiers

PMID32430573
OpenAlexW3026537183

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.